Related Experiment Video
Updated: May 17, 2026
07:12
Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
Published on: August 2, 2021
Tailored therapy: matching the method to the patient
Etienne Macedo1, Ravindra L Mehta
1Division of Nephrology, University of São Paulo, São Paulo, Brazil.
Blood Purification
|October 26, 2012
Summary
Deciding on dialysis initiation and modality for critically ill patients with acute kidney injury involves many factors. This review covers renal support goals, dialysis techniques, and strategies for personalized treatment in intensive care units.
Area of Science:
- Nephrology
- Critical Care Medicine
- Renal Replacement Therapy
Background:
- Acute kidney injury (AKI) is common in critically ill patients.
- Decisions regarding dialysis initiation and modality are complex and vary globally.
- Current practices rely on patient condition, resources, and local experience.
Purpose of the Study:
- To review therapeutic goals for renal support in AKI.
- To compare advantages and disadvantages of different dialysis modalities.
- To provide strategies for individualizing renal support timing and modality selection.
Main Methods:
- Literature review of therapeutic goals in renal support.
- Analysis of the pros and cons of various dialysis techniques.
- Description of strategies for timing and modality matching.
Main Results:
- Therapeutic goals of renal support are multifaceted.
- Different dialysis modalities offer distinct benefits and drawbacks.
- Individualized strategies can optimize renal support for ICU patients.
Conclusions:
- Optimizing renal support requires careful consideration of goals and techniques.
- Personalized strategies for dialysis initiation and modality selection are crucial.
- Further research may refine best practices for AKI management in critical care.
Related Concept Videos
01:24Dosage Regimen: Individualization
Individualization in dosing regimens is the customization of medication doses for individual patients. Its necessity arises from the goal of maximizing therapeutic benefits while minimizing risks. This approach is pivotal because human responses to drugs can vary widely; what is effective for one person may be inadequate or excessive for another. Interpatient (intersubject) variability refers to differences in drug responses between individuals, while intrapatient (intrasubject) variability...
02:50Combination Therapies and Personalized Medicine
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
02:50Combination Therapies and Personalized Medicine
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
01:28Drug Therapy
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
01:26Therapeutic Drug Monitoring: Drug Analysis Methods
Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood or body tissues to tailor drug therapy effectively. This monitoring is critical for managing drugs with narrow therapeutic indices like digoxin and phenytoin, ensuring they are both safe and effective. For instance, monitoring theophylline levels in asthma patients involves precision and sensitivity to adjust doses according to individual responses to therapy, ensuring efficacy and...
01:28Dosage Regimens: Designs and Approaches
Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...