Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
Vaccinations01:51

Vaccinations

Overview
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effect of pre-booked appointments on COVID-19 vaccine uptake among previously vaccinated older adults during the 2023 autumn campaign in the Netherlands: a regression discontinuity analysis.

Vaccine·2026
Same author

Patient-reported outcome measures of percutaneous nephrostomy vs JJ stent in obstructive urolithiasis: results of the STent Or NEphrostomy (STONE) randomised controlled trial.

BJU international·2026
Same author

[A teenager with hyperpigmentation].

Nederlands tijdschrift voor geneeskunde·2026
Same author

COVID-19 Vaccine Effectiveness in Patients With Hematologic Malignancies: A Nationwide Cohort Study.

The Journal of infectious diseases·2025
Same author

Risk factors for invasive group A streptococcal infection in children aged 6 months to 5 years: a case-control study, the Netherlands, February-May 2023.

Epidemiology and infection·2025
Same author

Innate immune response after BNT162b2 COVID-19 vaccination associates with reactogenicity.

Vaccine: X·2024

Related Experiment Video

Updated: May 17, 2026

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
12:42

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo

Published on: January 7, 2019

[Mumps makes a comeback].

Wim Opstelten1, Susan J M Hahné, J Herman van Roijen

  • 1Nederlands Huisartsen Genootschap, Utrecht, the Netherlands. w.opstelten@nhg.org

Nederlands Tijdschrift Voor Geneeskunde
|October 26, 2012
PubMed
Summary
This summary is machine-generated.

Mumps outbreaks are occurring in vaccinated individuals due to waning immunity and crowding. Early recognition of mumps and its complications is crucial for effective surveillance and vaccination strategies.

More Related Videos

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
08:32

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

Published on: March 2, 2014

Merkel Cell Polyomavirus Infection and Detection
13:45

Merkel Cell Polyomavirus Infection and Detection

Published on: February 7, 2019

Related Experiment Videos

Last Updated: May 17, 2026

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
12:42

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo

Published on: January 7, 2019

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
08:32

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

Published on: March 2, 2014

Merkel Cell Polyomavirus Infection and Detection
13:45

Merkel Cell Polyomavirus Infection and Detection

Published on: February 7, 2019

Area of Science:

  • Epidemiology
  • Immunology
  • Public Health

Background:

  • The National Immunisation Programme in the Netherlands introduced mumps vaccination in 1987, leading to a significant decline in incidence.
  • Since 2009, recurrent mumps outbreaks have been observed, primarily affecting student populations.

Observation:

  • Case studies include a vaccinated adult with uncomplicated mumps, a vaccinated student with mumps orchitis, and an unvaccinated adolescent with permanent deafness.
  • Mumps predominantly impacts individuals vaccinated over a decade ago, suggesting potential issues with vaccine-induced immunity.

Findings:

  • Outbreaks are attributed to factors such as incomplete vaccine protection, waning immunity over time, and close-contact settings like universities.
  • The study highlights the occurrence of severe complications, including orchitis and deafness, even in vaccinated individuals.

Implications:

  • Effective outbreak response requires robust surveillance, investigation, and targeted catch-up vaccination campaigns for students.
  • Recognizing mumps and its complications is vital for informing potential adjustments to mumps vaccination recommendations and policies.