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Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
Human brucellosis in Tuzla Canton
Sead Ahmetagic1, Nijaz Tihic, Aldina Ahmetagic
1Clinic for Infectious Disease, University Clinical Centre Tuzla, Tuzla, Bosnia and Herzegovina. sead.ahmetagic@ukctuzla.ba
Medical Archives (Sarajevo, Bosnia and Herzegovina)
|October 27, 2012
Summary
Human brucellosis remains a significant public health concern in Bosnia and Herzegovina, particularly in the Tuzla Canton. This study details clinical and epidemiological features of brucellosis cases from 2000-2010.
Area of Science:
- Infectious Diseases
- Epidemiology
- Public Health
Background:
- Human brucellosis prevalence in Bosnia and Herzegovina peaked in 2008, with 994 national cases and 104 in Tuzla Canton.
- The disease poses a growing public health challenge in the region.
Purpose of the Study:
- To analyze the clinical and epidemiological characteristics of human brucellosis.
- To examine patient data from the University Clinical Center Tuzla between 2000 and 2010.
Main Methods:
- Retrospective analysis of clinical symptoms, laboratory results, X-ray findings, treatments, and outcomes.
- Diagnosis confirmed by anamnesis, clinical presentation, blood culture, and serological tests.
Main Results:
- Most patients (93.18%) were from rural areas, predominantly males (79.54%) aged 30-39.
- Common symptoms included fever, joint pain, night sweats, anorexia, headaches; key findings were elevated ESR, CRP, and anemia.
- Treatment involved antibiotic combinations (gentamicin/streptomycin with doxycycline for adults; gentamicin with trimethoprim-sulfamethoxazole for children) for at least 6 weeks.
Conclusions:
- Brucellosis is an escalating public health issue in Tuzla Canton and Bosnia and Herzegovina.
- Complications occurred in 20.45% of patients, with relapses in 14.20% and chronic forms in 5.11%.
- No lethal outcomes were reported.
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