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Published on: February 15, 2018
[Progress on miRNA in mammal breast milk]
Xue-Mei Song1, Jun-Fang Jiang, Yong-Qing Jiang
1Institute of Animal Husbandry and Veterinary, Zhejiang Academy of Agricultral Scicences, Hangzhou 310021, China. songxuemei@yeah.net
Yi Chuan = Hereditas
|October 27, 2012
Summary
MicroRNAs (miRNAs) are found in mammal milk, suggesting they can transfer to offspring via lactation. This opens new research avenues into generational miRNA regulation.
Area of Science:
- Molecular Biology
- Genetics
- Biochemistry
Context:
- MicroRNAs (miRNAs) are crucial regulators in eukaryotes.
- miRNAs are present in various animal body fluids like serum, plasma, saliva, and urine.
- Recent findings show miRNAs also exist in human and cow breast milk.
Purpose:
- To introduce the methods for detecting and isolating miRNAs in mammal milk.
- To describe the format of miRNAs within milk.
- To review the functions of specific milk miRNAs.
Summary:
- This study details the identification and isolation of microRNAs (miRNAs) in mammal milk.
- It explores the structure of milk miRNAs and reviews the roles of several key miRNAs.
- The research highlights the potential for miRNA transfer to offspring through lactation.
Impact:
- Establishes milk miRNAs as a potential mechanism for intergenerational molecular transfer.
- Suggests a new paradigm for studying regulatory functions of miRNAs across generations.
- Identifies future research directions and challenges in the field of milk miRNAs.
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