Related Experiment Video

Updated: May 17, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Ring infiltrate in staphylococcal keratitis

Batriti S Wallang1, Sujata Das, Savitri Sharma

  • 1Cornea and Anterior Segment Service, L. V. Prasad Eye Institute, Bhubaneswar, Odisha, India.

Journal of Clinical Microbiology
|October 27, 2012
PubMed

Insights

A Staphylococcus infection resistant to fluoroquinolones caused a corneal ring infiltrate. Surgical intervention, penetrating keratoplasty, was necessary due to the infection

Area of Science:

  • Ophthalmology
  • Microbiology
  • Infectious Diseases

Background:

  • Corneal infections can lead to sight-threatening conditions.
  • Antibiotic resistance is a growing concern in treating microbial keratitis.

Observation:

  • A patient presented with a corneal ring infiltrate.
  • Smear and culture tests revealed Staphylococcus species resistant to fluoroquinolones.

Findings:

  • The Staphylococcus isolate demonstrated resistance to fluoroquinolone antibiotics.
  • The corneal infiltrate was recalcitrant to medical management.

Implications:

  • Staphylococcal keratitis can manifest as a ring infiltrate.
  • Therapeutic penetrating keratoplasty may be required for resistant cases.
  • This case highlights the challenges of fluoroquinolone-resistant Staphylococcus infections in ophthalmology.

More Related Videos

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures04:48

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures

Published on: November 22, 2024

Related Concept Videos

Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...