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Neisseria meningitidis Infection of Induced Pluripotent Stem-Cell Derived Brain Endothelial Cells
Published on: July 14, 2020
Head and neck emergencies: bacterial meningitis, encephalitis, brain abscess, upper airway obstruction, and jugular
Catherine J Derber1, Stephanie B Troy
1Department of Internal Medicine, Division of Infectious Diseases, Eastern Virginia Medical School, Norfolk, VA, USA. derbercj@evms.edu
Abstract:
Head and neck infectious disease emergencies can be rapidly fatal without prompt recognition and treatment. Empiric intravenous (IV) antibiotics should be initiated immediately in any patient with suspected bacterial meningitis, and IV acyclovir in any patient with suspected encephalitis. Surgical intervention is often necessary for brain abscesses, epiglottitis, and Ludwig's angina. A high index of suspicion is often needed to diagnose epiglottitis, Ludwig's angina, and Lemierre's syndrome. Brain infections can have high morbidity among survivors. In this article, the causes, diagnostic tests, treatment, and prognosis are reviewed for some of the more common head and neck infectious disease emergencies.
Insights
Prompt recognition and treatment of head and neck infectious emergencies are critical. Immediate empiric antibiotics for meningitis and acyclovir for encephalitis, alongside potential surgical interventions, are vital for patient survival and reduced morbidity.
Area of Science:
- Infectious Diseases
- Emergency Medicine
- Neurosurgery
Background:
- Head and neck infectious disease emergencies pose significant risks, including rapid fatality.
- Prompt diagnosis and intervention are crucial for managing potentially life-threatening conditions.
Purpose of the Study:
- To review the causes, diagnostic methods, treatment strategies, and prognoses of common head and neck infectious disease emergencies.
- To emphasize the importance of early recognition and management in critical care settings.
Main Methods:
- Literature review of common head and neck infectious disease emergencies.
- Discussion of diagnostic criteria and therapeutic approaches, including medical and surgical interventions.
Main Results:
- Bacterial meningitis requires immediate empiric intravenous (IV) antibiotics.
- Suspected encephalitis necessitates prompt IV acyclovir administration.
- Surgical intervention is frequently required for brain abscesses, epiglottitis, and Ludwig's angina.
Conclusions:
- A high index of suspicion is essential for diagnosing conditions like epiglottitis, Ludwig's angina, and Lemierre's syndrome.
- Timely and appropriate treatment can mitigate high morbidity associated with brain infections.
- Effective management of these emergencies is key to improving patient outcomes.
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