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Oxalosis and livedo reticularis
E Jorquera-Barquero1, M C Súarez-Marrero, F Fernández Girón
1Servicio de Dermatología Médico-Quirúrgica y Venereología, Hospital Juan Ramón Jiménez, Huelva, España.
Actas Dermo-Sifiliograficas
|October 30, 2012
Summary
Oxalosis, caused by calcium oxalate deposition, can affect skin blood vessels, leading to livedo reticularis and ulcers. This case highlights oxalate vasculopathy in a patient with end-stage renal disease.
Area of Science:
- Nephrology
- Dermatology
- Pathology
Background:
- Oxalosis involves calcium oxalate deposition in extrarenal tissues, impacting organs like skin.
- Skin vascular involvement can manifest as livedo reticularis, ulcers, and gangrene.
Observation:
- A 60-year-old woman with end-stage renal failure developed sudden-onset, tender, red-violaceous skin lesions.
- These lesions progressed to ulceration, clinically resembling livedo reticularis.
Findings:
- Skin biopsy confirmed oxalate vasculopathy, a rare manifestation of oxalosis.
- The patient's history included recurrent renal lithiasis and long-term dialysis.
Implications:
- This case underscores the importance of recognizing oxalate vasculopathy in dialysis patients.
- Differentiating oxalosis from calciphylaxis is crucial for appropriate management and therapeutic options.
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