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Outbreak of Pseudomonas fluorescens bloodstream infection in a coronary care unit
N Benito1, B Mirelis, M Luz Gálvez
1Infectious Diseases Unit, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. nbenito@santpau.cat
Abstract:
An outbreak of Pseudomonas fluorescens infection in six patients in a coronary care unit was associated with a source not previously reported, namely the ice bath used for cardiac output determinations. Outbreaks of pseudobacteraemia caused by P. fluorescens and occasional blood transfusion-associated bloodstream infection (BSI) have been described. However, during the last two decades, two outbreaks of P. fluorescens BSI have been described and this article reports a third. Isolation of P. fluorescens in blood cultures must alert clinicians to the possibility of contamination of infusate, lock solutions or catheter flush.
Insights
A Pseudomonas fluorescens outbreak in a coronary care unit was linked to an ice bath used for cardiac output measurements. This highlights a new source for pseudobacteraemia and bloodstream infections (BSI).
Area of Science:
- Infectious Diseases
- Clinical Microbiology
Background:
- Pseudomonas fluorescens (P. fluorescens) bloodstream infections (BSI) are uncommon.
- Previous outbreaks have been linked to contaminated medical products.
- A novel source of P. fluorescens infection requires identification.
Purpose of the Study:
- To report a third outbreak of P. fluorescens BSI in two decades.
- To identify the source of infection in six patients in a coronary care unit.
- To alert clinicians to potential contamination risks.
Main Methods:
- Case identification in a coronary care unit.
- Microbiological investigation to identify the causative agent.
- Environmental sampling to pinpoint the source of contamination.
Main Results:
- Six patients in the coronary care unit developed P. fluorescens infection.
- The outbreak was traced to an ice bath used for cardiac output determinations.
- This represents a previously unreported source for P. fluorescens pseudobacteraemia.
Conclusions:
- Ice baths used for cardiac output measurements can be a source of P. fluorescens contamination.
- Clinicians should consider contamination of infusates, lock solutions, or catheter flush when P. fluorescens is isolated from blood cultures.
- Enhanced vigilance and infection control measures are necessary to prevent similar outbreaks.
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