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Related Concept Videos

DNA as a Genetic Template02:05

DNA as a Genetic Template

Two structural features of the DNA molecule provide a basis for the mechanisms of heredity: the four nucleotide bases and its double-stranded nature. The Watson-Crick model of double-helical DNA structure, proposed in 1952, drew heavily upon the X-ray crystallography work of researchers Rosalind Franklin and Maurice Wilkins. Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine for their work in 1962. Franklin was, controversially, excluded from the prize for...
DNA as a Genetic Template02:05

DNA as a Genetic Template

Two structural features of the DNA molecule provide a basis for the mechanisms of heredity: the four nucleotide bases and its double-stranded nature. The Watson-Crick model of double-helical DNA structure, proposed in 1952, drew heavily upon the X-ray crystallography work of researchers Rosalind Franklin and Maurice Wilkins. Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine for their work in 1962. Franklin was, controversially, excluded from the prize for...
DNA Topoisomerases02:02

DNA Topoisomerases

Topoisomerases are enzymes that relax overwound DNA molecules during various cell processes, including DNA replication and transcription. These enzymes regulate positive and negative DNA supercoiling without changing the nucleotide sequence. DNA overwinding in a clockwise direction results in positively supercoiled DNA, whereas underwinding in a counterclockwise direction produces negatively supercoiled DNA.
Types and Mechanism of action
Topoisomerases are divided into two main types.  Type I...
The DNA Helix01:16

The DNA Helix

Overview
The DNA Helix01:07

The DNA Helix

Deoxyribonucleic acid, or DNA, is the genetic material responsible for passing traits from generation to generation in all organisms and most viruses. DNA is composed of two strands of nucleotides that wind around each other to form a spring-like structure called a double helix. However, the double helix is not perfectly symmetrical. Instead, there are regularly occurring grooves in the structure. The major groove occurs where the sugar-phosphate backbones are relatively far apart. This space...
The DNA Helix01:16

The DNA Helix

Overview

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Related Experiment Video

Updated: May 17, 2026

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes
08:35

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes

Published on: July 17, 2021

To DNA, all information is equal.

Lau Sennels1, Thomas Bentin

  • 1Institute of Cell Biology, University of Edinburgh, Edinburgh, UK. lau@sennels.dk

Artificial DNA, PNA & XNA
|October 30, 2012
PubMed
Summary

Scientists encoded binary data in DNA, significantly boosting information storage density. While the technology is nascent, DNA offers a durable, high-capacity solution for long-term data archiving.

Area of Science:

  • Biotechnology
  • Information Science
  • Genomics

Background:

  • The demand for data storage is rapidly increasing.
  • DNA offers a potential high-density information storage medium.

Purpose of the Study:

  • To demonstrate the feasibility of encoding, storing, and retrieving binary data using DNA oligonucleotides.
  • To assess the potential of DNA as a long-term information storage solution.

Main Methods:

  • Encoding binary data into a library of oligonucleotides.
  • Storing the synthesized DNA molecules.
  • Retrieving and decoding the stored binary data from the DNA library.

Main Results:

  • Successfully encoded, stored, and retrieved binary data from DNA.
Keywords:
DNAbinary encodingbitbyteinformation storage in DNA

Related Experiment Videos

Last Updated: May 17, 2026

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes
08:35

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes

Published on: July 17, 2021

  • Achieved a significant increase in information density compared to previous methods.
  • Demonstrated compatibility with large-scale DNA sequencing and synthesis technologies.

    • Conclusions:

    • DNA can serve as a high-density information storage medium.
    • The technology has the potential for long-term data archiving over centuries.
    • Further development is needed to overcome current limitations and realize its full potential.