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The role of attachment style and depression in patients with hepatitis C
Sanjeev Sockalingam1, Diana Blank, Abdulqader Al Jarad
1Department of Psychiatry, Program in Medical Psychiatry, University Health Network, University of Toronto, Toronto, ON, Canada. sanjeev.sockalingam@uhn.ca
Insights
Fearful attachment styles are linked to higher depression in chronic hepatitis C virus (HCV) patients. While depression, fatigue, and pain interconnect, attachment style primarily impacts depressive symptoms in HCV management.
Area of Science:
- Psychiatry and Psychology
- Hepatology
- Clinical Research
Background:
- Chronic hepatitis C virus (HCV) infection frequently presents with a triad of depression, pain, and fatigue.
- Psychological and interpersonal factors are suspected to influence this symptom triad, but their precise role remains unclear.
- Understanding these influences is crucial for comprehensive patient care in HCV management.
Purpose of the Study:
- To investigate the relationship between attachment styles and depressive and physical symptoms in patients with chronic HCV infection.
- To identify specific attachment patterns associated with symptom burden in this population.
- To explore the interplay between attachment, depression, fatigue, and physical symptoms in HCV.
Main Methods:
- Retrospective study involving 99 HCV-infected patients over 18 months.
- Assessment using the Hamilton Depression Rating Scale (HDRS), Fatigue Severity Scale, Patient Health Questionnaire-15 (physical symptoms), and Relationship Questionnaire (attachment style).
- Statistical analysis included ANOVA to compare attachment styles and Pearson correlations to assess symptom associations.
Main Results:
- Approximately 15% of patients exhibited a fearful attachment style.
- Patients with a fearful attachment style reported significantly higher depressive symptoms compared to those with a secure attachment style (p=0.025).
- No significant differences in physical or fatigue symptoms were found across attachment styles; however, depression scores correlated strongly with fatigue and physical symptoms (p<0.001).
Conclusions:
- While depressive, physical, and fatigue symptoms are interconnected in HCV patients, only depressive symptoms appear significantly influenced by attachment style extremes.
- Fearful attachment may identify HCV patients at higher risk for depression, potentially impacting their engagement in care and symptom management.
- Screening for attachment and relationship styles could aid in identifying and supporting HCV-infected individuals vulnerable to depression.
Abstract:
Patients infected with chronic hepatitis C virus (HCV) commonly suffer from the triad of depression, pain and fatigue. This symptom triad in HCV is likely influenced by additional psychological and interpersonal factors, although the relationship is not clearly understood. This retrospective study aimed to characterize the relationship between attachment style and depressive and physical symptoms in the HCV-infected population. Over 18 months, 99 consecutively referred HCV infected patients were assessed with the Hamilton Depression Rating Scale (HDRS), Fatigue Severity Scale, Patient Health Questionnaire-15 for physical symptoms and the Relationship Questionnaire for attachment style. An ANOVA was used to identify differences between attachment styles and Pearson correlations were used to evaluate the association between depression, fatigue and physical symptoms. Approximately 15 % of patients in the sample had a fearful attachment style. Patients with fearful attachment style had significantly higher depressive symptoms compared to a secure attachment style (p = .025). No differences in physical and fatigue symptoms were observed between attachment styles. Further, HDRS scores were significantly associated with fatigue scores (p < .001) and physical symptoms (p < .001), reinforcing the relationship between these symptom domains in HCV-infected patients. Although depressive, physical and fatigue symptoms are inter-related in HCV-infected patients, our study results suggest that only depressive symptoms were influenced by the extremes of attachment style. Screening of relationship styles may identify at-risk HCV-infected individuals for depression who may have difficulty engaging in care and managing physical symptoms.
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