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Updated: Aug 1, 2026

Measurement of mRNA Decay Rates in Saccharomyces cerevisiae Using rpb1-1 Strains
Published on: December 13, 2014
Nonsense suppressors partially revert the decrease of the mRNA level of a nonsense mutant allele in yeast
1Institut für Mikrobiologie, Technische Hochschule Darmstadt, Federal Republic of Germany.
Abstract:
suc2 degrees is a naturally occurring amber mutant allele of the yeast invertase structural gene SUC2. Strains carrying suc2 degrees had only 10% of the wild type invertase-specific mRNA level. Amber suppressors, which allowed suc2 degree strains to ferment sucrose caused an increase of the SUC-specific mRNA level.
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