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Updated: May 17, 2026

Quantitative Assessment Protocol for Facial Soft Tissue Volumetric Changes with Stereophotogrammetry
Published on: December 9, 2025
Three-dimensional soft tissue analysis for the evaluation of facial asymmetry in normal occlusion individuals
Hyeon-Shik Hwang1, Donghui Yuan, Kweon-Heui Jeong
1Department of Orthodontics, 2nd Stage of Brain Korea 21, School of Dentistry, Dental Science Research Institute, Chonnam National University, Gwangju, Korea.
Objective:
To identify the right and left difference of the facial soft tissue landmarks three-dimensionally from the subjects of normal occlusion individuals.
Materials And Methods:
Cone-beam computed tomography (CT) scans were obtained in 48 normal occlusion adults (24 men, 24 women), and reconstructed into 3-dimensional (3D) models by using a 3D image soft ware. 3D position of 27 soft tissue landmarks, 9 midline and 9 pairs of bilateral landmarks, were identified in 3D coordination system, and their right and left differences were calculated and analyzed.
Results:
The right and left difference values derived from the study ranged from 0.6 to 4.6 mm indicating a high variability according to the landmarks. In general, the values showed a tendency to increase according to the lower and lateral positioning of the landmarks in the face. Overall differences were determined not only by transverse differences but also by sagittal and vertical differences, indicating that 3D evaluation would be essential in the facial soft tissue analysis.
Conclusions:
Means and standard deviations of the right and left difference of facial soft tissue landmarks derived from this study can be used as the diagnostic standard values for the evaluation of facial asymmetry.

