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Updated: May 17, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
Published on: March 14, 2025
[Skin necrosis resulting from the extravasation of intravenous injections]
Soumaya Ikhefoulma1, Abelhamid Mahiou, Isabelle Perillat
1Service de gériatrie, hôpital René Muret (AP-HP), Sevran. smikhefoulma@yahoo.fr
Abstract:
Extravasation is the diffusion of a product injected intravenously into the perivascular or subcutaneous spaces. Skin necrosis of iatrogenic origin can be observed for example with a subcutaneous perfusion of solution containing potassium chloride or the extravasation of 30% hypertonic glucose serum. Whenever a product is injected, the administration route for which the product has obtained marketing authorisation must be respected and a perfusion time of at least 4 to 5 hours per litre of solution perfused must be observed.
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