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Updated: May 17, 2026
06:46
Measurement of Tactile Allodynia in a Murine Model of Bacterial Prostatitis
Published on: January 16, 2013
[Chronic infection urethroprostatit: a new look at old problem].
Urologiia (Moscow, Russia : 1999)
|November 3, 2012
Summary
Adding the immunomodulator Lavomax to basic therapy significantly improved immune function and cleared infections in men with chronic urethroprostatitis. This combination therapy offers a pathogenetically substantiated approach for treating chlamydial and mycoplasmal infections.
Area of Science:
- Urology
- Immunology
- Infectious Diseases
Background:
- Chronic urethroprostatitis, often linked to chlamydial and mycoplasmal infections, presents with prostate inflammation and immune disturbances.
- Standard treatments may not fully restore immune function or eradicate persistent pathogens.
Purpose of the Study:
- To evaluate the efficacy of an immunomodulator, Lavomax, combined with basic therapy for chronic urethroprostatitis caused by chlamydial and mycoplasmal infections.
- To assess the impact of this combined therapy on immune parameters and pathogen elimination.
Main Methods:
- A randomized study involving 114 men with chronic urethroprostatitis compared basic therapy alone versus basic therapy plus Lavomax.
- Investigations included PCR, ultrasound, and immunological markers (cellular and humoral immunity).
Main Results:
- The group receiving Lavomax showed significant normalization of cellular immunity, including improved neutrophil function and lymphocyte subpopulations.
- This group also exhibited normalized immunoglobulin and cytokine levels (IgA, IgG, IL-8, INF-gamma) and faster pathogen elimination.
- Clinical symptoms resolved more effectively in the Lavomax group.
Conclusions:
- Immunomodulator Lavomax is a pathogenetically substantiated addition to the comprehensive treatment of chronic urethroprostatitis associated with chlamydial and mycoplasmal infections.
- Combining Lavomax with basic therapy enhances immune recovery and improves treatment outcomes.
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