Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists01:30

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function. They...
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Jugular Venous Compression Collar for Prevention of Brain Injury due to Repetitive Head Impact and Concussion in Sport: A Scoping Review.

Sports health·2026
Same author

Test-retest reliability of the SCAT6 tandem gait and cognitive components among professional hockey players.

British journal of sports medicine·2026
Same author

Cognitive behavioral therapy for insomnia for individuals with multiple sclerosis (CALM): A randomized control trial protocol.

Contemporary clinical trials communications·2026
Same author

The TRaditional versus Early Aggressive Therapy for Multiple Sclerosis (TREAT-MS) trial: design and baseline characteristics of participants.

Contemporary clinical trials·2025
Same author

A description of processing speed, learning and memory in people with multiple sclerosis aged 55.

Multiple sclerosis and related disorders·2025
Same author

Mechanisms of Action of Combination Motivational Interviewing-Cognitive Behavior Therapy for Reversing Medication Non-Adherence in Patients With Multiple Sclerosis.

Journal of clinical psychology·2025
Same journal

Clinical neuropsychological evaluation of patients referred from a post-COVID subspeciality clinic.

The Clinical neuropsychologist·2026
Same journal

Cardiometabolic burden and cognitive profiles in adults 55.

The Clinical neuropsychologist·2026
Same journal

Unraveling delusional misidentification: A neuropsychological and experimental exploration of a new case of reduplication syndrome.

The Clinical neuropsychologist·2026
Same journal

Characteristics and clinical correlates of objective medication adherence in older adults with cognitive impairment.

The Clinical neuropsychologist·2026
Same journal

Concordance between domain-based neuropsychological profiles and clinical phenotypes in young-onset dementia.

The Clinical neuropsychologist·2026
Same journal

Exploring the relationship between self-report and performance-based measures of impulsivity.

The Clinical neuropsychologist·2026
See all related articles

Related Experiment Video

Updated: May 17, 2026

The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

How patients with multiple sclerosis perceive cognitive slowing.

Brandon L Roberg1, Jared M Bruce, Chris T Lovelace

  • 1Department of Psychology, University of Missouri-Kansas City, Kansas City, MO 64110, USA. brucejm@umkc.edu

The Clinical Neuropsychologist
|November 3, 2012
PubMed
Summary
This summary is machine-generated.

Multiple sclerosis patients perceive significant cognitive slowing, impacting daily life. This perceived deficit is linked to anxiety and motor speed, not objective tests.

More Related Videos

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
07:30

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
07:42

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

Related Experiment Videos

Last Updated: May 17, 2026

The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
07:30

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
07:42

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Clinical Neurology

Background:

  • Slowed processing speed is a primary cognitive deficit in multiple sclerosis (MS).
  • Patient perception of this cognitive deficit remains understudied.
  • Understanding subjective experiences is crucial for comprehensive MS care.

Purpose of the Study:

  • To investigate perceived processing speed difficulties in individuals with MS.
  • To explore the relationship between perceived cognitive slowing and other psychological and motor factors.
  • To compare patient perceptions with objective measures of processing speed.

Main Methods:

  • Involved clinical and community samples of MS patients and control groups.
  • Utilized self-report questionnaires to assess perceived processing speed.
  • Correlated perceived difficulties with measures of impulsivity, motor speed, anxiety, and introversion.
  • Compared perceived processing speed with objective cognitive assessments.

Main Results:

  • MS patients reported significantly higher processing speed difficulties than controls.
  • Perceived processing speed deficits were associated with impulsivity, slowed motor speed, anxiety, and introversion.
  • Perceived processing speed did not strongly correlate with objective processing speed measures.
  • Cognitive slowing perceptions were most related to motor task performance and anxiety levels.

Conclusions:

  • MS patients experience and perceive significant cognitive slowing.
  • Subjective perceptions of cognitive slowing are influenced by factors like anxiety and motor function.
  • Clinical interventions should consider patient-reported cognitive experiences and anxiety management.
  • Educating patients on the distinction between subjective perception and objective performance is beneficial.