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Neoplasms of the appendix: current treatment guidelines.
Suven Shankar1, Panayotis Ledakis, Hatem El Halabi
1Department of Surgical Oncology, Institute for Cancer Care, Mercy Medical Center, Baltimore, MD 21202, USA.
Hematology/Oncology Clinics of North America
|November 3, 2012
Summary
This review updates physicians on appendiceal neoplasms management. It covers diagnosis, surgical techniques, chemotherapy, and the standard of care for peritoneal carcinomatosis using cytoreductive surgery and hyperthermic intraperitoneal therapy.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Oncology
Background:
- Appendiceal neoplasms are rare but require specific management strategies.
- Accurate diagnosis and staging are crucial for effective treatment.
- Peritoneal carcinomatosis from appendiceal tumors presents unique challenges.
Purpose of the Study:
- To provide an updated overview of current management for appendiceal neoplasms.
- To review clinical evidence for medical and surgical treatments.
- To detail the standard of care for peritoneal carcinomatosis.
Main Methods:
- Review of clinical evidence for medical and surgical treatments.
- Emphasis on presentation, diagnosis, and pathology.
- Detailed description of surgical techniques and systemic chemotherapy.
- Focus on cytoreductive surgery and hyperthermic intraperitoneal therapy (HIPEC).
Main Results:
- Appendiceal neoplasms require a multidisciplinary approach.
- Systemic chemotherapy has a role in select cases.
- Cytoreductive surgery and HIPEC are the standard of care for peritoneal carcinomatosis.
Conclusions:
- Optimal management of appendiceal neoplasms involves tailored surgical and medical strategies.
- HIPEC combined with cytoreductive surgery offers the best outcomes for peritoneal carcinomatosis.
- Continued research is needed to refine treatment protocols.
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