Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Focusing of Light in the Eye01:16

Focusing of Light in the Eye

Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
Accessory Structures of the Eye01:17

Accessory Structures of the Eye

Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Improve Cure Rate of Children with Retinoblastoma: The AMCC Programme in Sub-Saharan Africa.

Seminars in ophthalmology·2025
Same author

Differential Effect of Aldosterone or Mineralocorticoid Receptor Overexpression on Retinal Inflammation.

Investigative ophthalmology & visual science·2024
Same author

Treatment adherence in retinoblastoma: A retro-prospective cohort study in Ivory Coast and the Democratic Republic of Congo.

Cancer reports (Hoboken, N.J.)·2023
Same author

Conservative treatment using laser diode and systemic chemotherapy for early-stage bilateral retinoblastoma: A 14-year prospective cohort study.

Cancer reports (Hoboken, N.J.)·2023
Same author

Evaluating the baseline survival outcomes of the "six Global Initiative for Childhood Cancer index cancers" in Africa.

Pediatric hematology and oncology·2022
Same author

Hidden in the Eyes-Recurrence of Systemic Hemopathies Reportedly "In Remission": Six Cases and Review of Literature.

Medicina (Kaunas, Lithuania)·2022
Same journal

Tonographic outflow facility and intraocular pressure after standalone OMNI surgery.

Journal of glaucoma·2026
Same journal

Factors Associated With Retinal Nerve Fiber Layer Asymmetry in Primary Open-Angle Glaucoma Among Individuals of African Ancestry.

Journal of glaucoma·2026
Same journal

Haploinsufficiency of PITX2 in Four Chinese Families with Axenfeld-Rieger Syndrome.

Journal of glaucoma·2026
Same journal

Intraocular Pressure-Lowering Effect of Omidenepag Isopropyl as a Predictor for the Efficacy of Laser Trabeculoplasty.

Journal of glaucoma·2026
Same journal

Comparative Outcomes Between Micropulse and Slow-Coagulation Transscleral Cyclophotocoagulation in Eyes With Good Visual Acuity.

Journal of glaucoma·2026
Same journal

Machine Learning With Optical Coherence Tomography for Glaucoma Diagnosis.

Journal of glaucoma·2026
See all related articles

Related Experiment Video

Updated: May 17, 2026

Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

A ciliary body tumor preventing angle closure.

Chadi Mehanna1, Laurence Desjardins, Michel Puech

  • 1*INSERM, UMRS-872, Centre de Recherche des Cordeliers, Team 17, Paris Descartes University †University of Pierre and Marie Curie ‡SISENE Ophthalmology, Pépinière Paris Santé, Cochin Hospital §Department of Ophthalmology, Assistance Publique-Hôpitaux de Paris, Hôtel-Dieu Hospital ∥Department of Ocular Oncology, Institut Curie ¶Centre Explore Vision #Centre d'Ophtalmologie du Trocadéro, Paris, France.

Journal of Glaucoma
|November 3, 2012
PubMed
Summary
This summary is machine-generated.

A ciliary body tumor caused angle closure glaucoma in one eye and partial closure in the other. Ultrasound biomicroscopy revealed the tumor

Related Experiment Videos

Last Updated: May 17, 2026

Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Area of Science:

  • Ophthalmology
  • Medical Imaging

Background:

  • Angle closure glaucoma is an ocular emergency.
  • Early diagnosis and treatment are crucial for vision preservation.

Observation:

  • A 60-year-old woman presented with advanced angle closure glaucoma in the right eye.
  • The left eye showed partial appositional closure with heavy pigmentation.
  • Ultrasound biomicroscopy identified a ciliary body tumor.

Findings:

  • The ciliary body tumor displaced the iris root, causing angle closure.
  • The tumor was associated with localized heavy pigmentation of the ciliary body band and trabecular meshwork.
  • The right eye had advanced glaucoma, while the left eye had partial closure without glaucoma.

Implications:

  • Ciliary body tumors can present with varied degrees of angle closure glaucoma.
  • Ultrasound biomicroscopy is valuable in diagnosing the cause of angle closure.
  • Prompt identification of underlying causes like tumors is essential for appropriate management.