Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Equilibrium and Balance

Equilibrium and Balance

The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...

Diabetes Insipidus II: Pathophysiology

Diabetes Insipidus II: Pathophysiology

Normally, water balance is maintained through three interconnected mechanisms: the hypothalamic thirst center, the synthesis and release of antidiuretic hormone (ADH, or vasopressin), and the kidneys' responsiveness to this hormone. ADH is synthesized in the hypothalamus, released from the posterior pituitary, and acts on the distal nephron, allowing water reabsorption and concentrated urine production.Diabetes Insipidus and Its TypesIn diabetes insipidus (DI), this regulatory system is...

Type I Diabetes II: Pathophysiology

Type I Diabetes II: Pathophysiology

Type 1 diabetes mellitus arises from an immune-mediated destruction of pancreatic β-cells, resulting in an absolute deficiency of insulin. This process develops in genetically susceptible individuals when autoimmunity, environmental exposures, and immunologic dysregulation converge to trigger a targeted attack on the insulin-producing cells of the pancreas. The β-cells are located within the islets of Langerhans and are essential for regulating blood glucose by facilitating cellular uptake of...

Pathophysiology of Diabetes

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...

Complications of Diabetes Mellitus

Complications of Diabetes Mellitus

Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency, resistance, or both. Prolonged hyperglycemia disrupts metabolic homeostasis and leads to acute and chronic complications.Acute ComplicationsAcute complications result from sudden metabolic imbalance.Diabetic ketoacidosis (DKA) mainly appears in type 1 diabetes but may also develop in type 2 diabetes, particularly under extreme stress. It arises from severe insulin deficiency,...

Diabetic Neuropathy

Diabetic Neuropathy

DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

CONGENITAL NASAL TERATOMA: Case Report.

Medical journal, Armed Forces India·2017

Same author

TRACHEOSTOMY COMPLICATIONS AND THEIR MANAGEMENT.

Medical journal, Armed Forces India·2017

Same author

MIDDLE EAR RECONSTRUCTION - OUR EXPERIENCE.

Medical journal, Armed Forces India·2017

Same author

HAEMOPTYSIS - INDICATIONS FOR BRONCHOSCOPY.

Medical journal, Armed Forces India·2017

Same author

METALLIC FOREIGN BODY IN LEFT MAIN BRONCHUS (A Case Report).

Medical journal, Armed Forces India·2017

Same author

NEW SUSPENSION DEVICE FOR LARYNGEAL ENDOSCOPIC PROCEDURES.

Medical journal, Armed Forces India·2017

Search research articles

Related Experiment Video

Updated: May 17, 2026

Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages

Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages

Published on: April 11, 2025

Vestibulo-cochlear functions in diabetes mellitus.

¹Department of ENT, Armed Forces Medical College, 411040 Pune.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India

|November 3, 2012

Summary

Diabetic patients often experience mild to moderate hearing loss, typically affecting high frequencies. This study found no evidence of vestibular dysfunction in individuals with diabetes.

Area of Science:

Otorhinolaryngology
Endocrinology
Audiology

Background:

Diabetes mellitus is a systemic disease with potential microvascular complications.
Hearing impairment is a recognized comorbidity in diabetic populations.
Vestibulocochlear dysfunction can impact quality of life.

Purpose of the Study:

To evaluate vestibulocochlear functions in diabetic individuals.
To determine the prevalence and characteristics of hearing loss in diabetes.
To investigate potential correlations between hearing loss and diabetes control or demographics.

Main Methods:

Comparative study involving 30 diabetic patients and 30 healthy controls.
Assessment of hearing thresholds, focusing on high-frequency ranges.

More Related Videos

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Published on: October 23, 2020

Related Experiment Videos

Last Updated: May 17, 2026

Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages

Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages

Published on: April 11, 2025

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Published on: October 23, 2020

Evaluation of vestibular function through standard clinical tests.

Main Results:

40% of diabetic participants exhibited mild to moderate hearing loss.
Hearing loss was predominantly bilateral, symmetrical, and cochlear in nature.
Higher incidence observed in older individuals and those with poorer glycemic control.

Conclusions:

Hearing loss is a significant concern in diabetic patients, particularly affecting high frequencies.
Glycemic control and age are associated with increased risk of hearing impairment.
Vestibular function appears unaffected in the studied diabetic cohort.