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Esthesioneuroblastoma - a rarity
R Arora1, P Singh, T N Shadangi
1Department of Endocrinology, P. G. I., Chandigarh.
Summary
A rare Esthesioneuroblastoma presented as a nasal mass causing vision loss and facial symptoms. Surgical removal, radiotherapy, and chemotherapy led to a positive outcome in this young male patient.
Area of Science:
- Neuro-oncology
- Ophthalmology
- Otorhinolaryngology
Background:
- Esthesioneuroblastoma is a rare malignant tumor arising from the olfactory epithelium.
- Olfactory neuroblastomas can present with varied symptoms including visual disturbances and nasal complaints.
- The suprasellar region is an uncommon location for this type of tumor.
Purpose of the Study:
- To report a case of Esthesioneuroblastoma with unusual presentation.
- To highlight the diagnostic challenges and treatment outcomes for this rare tumor.
Main Methods:
- A young male patient presented with a year of visual complaints and 3 months of epistaxis and nasal blockage.
- Clinical examination revealed bilateral proptosis and bitemporal hemianopia.
- Imaging studies including skull skiagram and computed tomography (CT) demonstrated a sellar and suprasellar mass with bony erosion.
Main Results:
- Partial excision of the suprasellar tumor was performed.
- Histopathological examination confirmed Esthesioneuroblastoma.
- The patient received adjuvant radiotherapy and chemotherapy (CCNU).
Conclusions:
- Esthesioneuroblastoma, though rare, should be considered in the differential diagnosis of sellar and suprasellar masses presenting with visual and nasal symptoms.
- Multimodal treatment including surgery, radiotherapy, and chemotherapy can achieve favorable outcomes.
