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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

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Published on: September 20, 2018

Melkersson-rosenthal syndrome.

D R Sharma1, S Resident, C Mohan

  • 1Indira Gandhi Medical College, Shimla.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
|November 3, 2012
PubMed
Summary

Melkersson-Rosenthal syndrome, a rare condition, presents with facial paralysis, lip/face swelling, and a fissured tongue. This case report details a rare presentation with alternating and bilateral facial paralysis, plus colonic dilation.

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Area of Science:

  • Neurology
  • Gastroenterology
  • Genetics

Background:

  • Melkersson-Rosenthal syndrome is a rare neurological disorder.
  • Characterized by recurrent unilateral or bilateral facial paralysis, fissured tongue, and facial edema.
  • The exact etiology remains unknown, but genetic factors are suspected.

Purpose of the Study:

  • To report a rare case of Melkersson-Rosenthal syndrome.
  • To highlight the classic and atypical findings in this patient.
  • To contribute to the understanding of this rare syndrome's clinical spectrum.

Main Methods:

  • Clinical case presentation.
  • Review of patient's medical history and symptoms.
  • Diagnostic evaluation including physical examination.

Main Results:

  • The patient presented with alternating facial paralysis, progressing to bilateral paralysis.
  • Classic symptoms of fissured tongue and facial/lip edema were present.
  • An atypical finding of sigmoid colon dilation without haustrations was observed.

Conclusions:

  • This case underscores the variability in Melkersson-Rosenthal syndrome presentation.
  • The presence of colonic abnormalities suggests a potential link between neurological and gastrointestinal manifestations.
  • Further research is needed to elucidate the syndrome's pathogenesis and associated conditions.