Extrathoracic castleman'S disease - presenting as a neck mass

Area of Science:

• Oncology
• Pathology
• Rare Diseases

Background:

• Castleman's disease (angiofollicular hyperplasia) is a complex lymphoproliferative disorder.
• Typically presents in the mediastinum, often associated with systemic conditions.
• Hyaline vascular, plasma cell, and hybrid types are recognized variants.

Purpose of the Study:

• To report a rare case of Castleman's disease.
• To describe the hyaline vascular type in an unusual location.
• To emphasize the importance of considering rare diagnoses in unexplained masses.

Main Methods:

• Case report of a 41-year-old male.
• Diagnostic evaluation of a left supraclavicular mass.
• Histopathological analysis confirming hyaline vascular Castleman's disease.

Main Results:

• A solitary hyaline vascular Castleman's disease was identified in the left supraclavicular region.
• The patient had no associated systemic illnesses or known comorbidities.
• The neck is an uncommon site for this rare disease presentation.

Conclusions:

• Castleman's disease can present as a localized neck mass.
• The hyaline vascular type may occur in extranodal locations without systemic involvement.
• This case underscores the diagnostic challenge posed by rare neck masses.