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Related Concept Videos

Larynx01:21

Larynx

The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids, corniculates, and...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Assessment of Airway, Skin Color, and Use of Accessory Muscles01:30

Assessment of Airway, Skin Color, and Use of Accessory Muscles

A thorough assessment of respiratory health is paramount in clinical settings to identify and manage respiratory distress and ensure adequate oxygenation. This article elaborates on the critical aspects of respiratory evaluation, including airway assessment, skin color examination, and the observation of accessory muscle use, which are integral to effectively diagnosing and managing patients with respiratory conditions.
Introduction
The initial evaluation of a patient's respiratory system...
Epistasis01:39

Epistasis

In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...

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Related Experiment Video

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A Heterotopic Mouse Model for Studying Laryngeal Transplantation
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A Heterotopic Mouse Model for Studying Laryngeal Transplantation

Published on: January 13, 2023

Laryngeal melanosis.

V Dutta1, P S Reddy

  • 1Department & Senior Advisor Pathololgy, Army Hospital, Delhi Cantt, 110 010 New Delhi.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
|November 3, 2012
PubMed
Summary
This summary is machine-generated.

Laryngeal melanosis, a rare condition, was identified in a 62-year-old male. While carcinoma in situ changes were noted histologically, the biopsy did not show definitive signs of malignancy.

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Area of Science:

  • Otolaryngology
  • Pathology
  • Oncology

Background:

  • Laryngeal melanosis is a rare condition characterized by melanin deposition in the larynx.
  • Pigmentation in the larynx can be associated with various conditions, including premalignant and malignant lesions.

Purpose of the Study:

  • To describe a case of laryngeal melanosis in a 62-year-old male.
  • To investigate the histological findings associated with laryngeal melanosis, particularly concerning premalignant changes.

Main Methods:

  • Case presentation of a 62-year-old male with laryngeal pigmentation.
  • Gross examination during laryngoscopy.
  • Histopathological analysis of biopsy tissue.

Main Results:

  • Laryngeal pigmentation was observed during gross examination via laryngoscopy.
  • Histological examination revealed a single focus of carcinoma in situ.
  • The biopsy tissue did not show definitive evidence of invasive malignancy.

Conclusions:

  • Laryngeal melanosis can present with histological findings suggestive of early neoplastic changes.
  • Further monitoring and investigation may be warranted in cases of laryngeal melanosis with associated premalignant changes.
  • This case highlights the importance of thorough histopathological evaluation in laryngeal melanosis.