Related Experiment Video

Updated: May 17, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
09:52

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Published on: March 9, 2018

Destructive aspergillosis

Surinder K Singhal1, Arjun Dass, G B Singh

  • 1Department of E.N.T., Government Medical College Hospital, 160047 Chandigarh, India.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
|November 3, 2012
PubMed

Insights

Mycotic infections of the sinuses are increasing, with Aspergillosis being common. This case highlights the destructive potential of Aspergillosis, causing significant maxillary bone destruction in a healthy individual.

Area of Science:

  • Otorhinolaryngology
  • Mycology
  • Pathology

Background:

  • Mycotic infections of the paranasal sinuses are increasingly prevalent.
  • Aspergillosis is the most frequent fungal infection affecting the nasal and sinus cavities.
  • The spectrum of Aspergillosis ranges from allergic to invasive and destructive forms.

Purpose of the Study:

  • To highlight the destructive potential of Aspergillosis, which is often overlooked in medical literature.
  • To report a rare case of Aspergillosis causing extensive maxillary destruction.

Main Methods:

  • Case report presentation.
  • Clinical and radiological evaluation of the patient.
  • Diagnostic confirmation of fungal infection.

Main Results:

  • A case of Aspergillosis presenting with massive destruction of the maxilla is described.
  • The patient was apparently healthy, indicating a potential for severe disease in immunocompetent individuals.
  • This presentation underscores the aggressive nature Aspergillosis can exhibit.

Conclusions:

  • Aspergillosis can cause severe destructive disease, comparable to mucormycosis.
  • The destructive potential of Aspergillosis warrants greater attention in clinical practice and research.
  • Early recognition and management are crucial for patients with destructive sinonasal fungal infections.
Keywords:
aspergillosisforehead flapmycotic infections

More Related Videos

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology08:01

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology

Published on: March 22, 2012

Related Concept Videos

Fungal Phylum Ascomycota01:28

Fungal Phylum Ascomycota

Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Biodeterioration01:28

Biodeterioration

Biodeterioration refers to the unwanted alteration of materials caused by microorganisms—especially fungi—which damage both organic substrates (paper, wood, textiles) and inorganic ones (stone, plaster, glass). Unlike abiotic decay, biodeterioration results from biological activity that produces physical disruption and chemical degradation.Physical deterioration occurs as fungal hyphae penetrate pores, cracks, and surface irregularities. Hyphal turgor pressure, thigmotropic growth along...
Fungal Phylum Basidiomycota01:26

Fungal Phylum Basidiomycota

Basidiomycota is a diverse phylum of fungi that includes ecologically significant decomposers such as white rot fungi, symbionts like mycorrhizal fungi, plant pathogens such as rusts and smuts, and edible species like Agaricus bisporus (the common button mushroom). These fungi play crucial roles in nutrient cycling, symbiotic relationships, and even human health. Their defining feature is the basidium, a microscopic club-shaped structure responsible for producing basidiospores.Fruiting Bodies...
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Antifungal Agents01:15

Antifungal Agents

Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to cholesterol contributes to...