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Screening for chronic comorbid diseases in people with HIV: the need for a strategic approach
B Peters1, F Post, A S Wierzbicki
1Department of Infectious Diseases, King's College London, London, UK. Barry.Peters@kcl.ac.uk
Insights
Chronic noninfectious diseases are a growing cause of death for people with HIV. A new screening tool is needed to manage risks effectively and improve patient care.
Area of Science:
- Public Health
- Infectious Diseases
- Chronic Disease Management
Background:
- Deaths from chronic noninfectious diseases are increasing among people with HIV, partly due to increased longevity from highly active antiretroviral therapy (HAART).
- HIV infection is linked to several chronic conditions, including cardiovascular disease, diabetes, renal, and bone diseases, often associated with modifiable risk factors.
- Current screening for these comorbidities is resource-limited and below standard in many HIV-infected populations, with few risk calculators adapted for HIV.
Purpose of the Study:
- To address the need for improved risk management of chronic noninfectious diseases in people with HIV.
- To develop a simple, unified screening approach for common comorbidities in HIV-infected individuals.
- To facilitate targeted management and improve patient-clinician communication regarding chronic disease risks.
Main Methods:
- The study proposes developing a unified screening tool by identifying overlapping risk factors for major chronic comorbid diseases relevant to HIV.
- The tool aims to identify patients needing further investigation and guide stepwise management.
- Health-based social networking is suggested as a platform for disseminating the tool and embedding educational support.
Main Results:
- A significant overlap in risk factors for cardiovascular disease, diabetes, renal, and bone diseases in people with HIV presents an opportunity for a simplified screening approach.
- The proposed screening tool can identify individuals requiring in-depth evaluation for lifestyle-related chronic diseases.
- Patient engagement in health promotion and the potential for using patient-centric screening measures are highlighted.
Conclusions:
- A simple, unified screening tool for chronic disease risk factors in people with HIV is feasible and could significantly improve risk management.
- This approach can lead to more targeted interventions and better patient outcomes.
- Integrating such tools within patient-centric platforms, like social networks, can enhance dissemination and support.
Abstract:
Among people living with HIV, the proportion of deaths attributed to chronic noninfectious comorbid diseases has increased over the past 15 years. This is partly a result of increased longevity in the era of highly active antiretroviral therapy (HAART), and also because HIV infection is related, causally or otherwise, to several chronic conditions. These comorbidities include conditions that are strongly associated with modifiable risk factors, such as cardiovascular disease (CVD), diabetes, and renal and bone diseases, and increasingly management guidelines for HIV recommend risk evaluation for these conditions. The uptake of these screening approaches is often limited by the resources required for their application, and hence the management of risk reduction in most HIV-infected populations falls below a reasonable standard. The situation is compounded by the fact that few risk calculators have been adjusted for specific use in HIV infection. There is substantial overlap of risk factors for the four common comorbid diseases listed above that are especially relevant in HIV infection, and this offers an opportunity to develop a simple screening approach that encompasses the key risk factors for lifestyle-related chronic disease in people with HIV infection. This would identify those patients who require more in-depth investigation, and facilitate a stepwise approach to targeted management. Such a tool could improve communication between patient and clinician. A significant proportion of people with HIV are sufficiently engaged with their care to participate in health promotion and take the lead in using patient-centric screening measures. Health-based social networking offers a mechanism for dissemination of such a tool and is able to embed educational messages and support within the process.
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