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Published on: October 25, 2024
An emboligenic pulmonary abscess leading to ischemic stroke and secondary brain abscess
Philipp Albrecht1, Mark Stettner, Leila Husseini
1Department of Neurology, Medical Faculty, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany. phil.albrecht@gmail.com
Background:
Ischemic stroke by septic embolism occurs primarily in the context of infective endocarditis or in patients with a right-to-left shunt and formation of a secondary cerebral abscess is a rare event. Erosion of pulmonary veins by a pulmonary abscess can lead to transcardiac septic embolism but to our knowledge no case of septic embolic ischemic stroke from a pulmonary abscess with secondary transformation into a brain abscess has been reported to date.
Case Presentation:
We report the case of a patient with a pulmonary abscess causing a septic embolic cerebral infarction which then transformed into a cerebral abscess. After antibiotic therapy and drainage of the abscess the patient could be rehabilitated and presented an impressive improvement of symptoms.
Conclusion:
Septic embolism should be considered as cause of ischemic stroke in patients with pulmonary abscess and can be followed by formation of a secondary cerebral abscess. Early antibiotic treatment and repeated cranial CT-scans for detection of a secondary abscess should be performed.
Insights
Septic embolism from a pulmonary abscess can cause ischemic stroke and brain abscess. Early antibiotic treatment and imaging are crucial for managing this rare condition.
Area of Science:
- Neurology
- Infectious Diseases
- Radiology
Background:
- Septic embolism is a known cause of ischemic stroke, often linked to infective endocarditis or right-to-left shunts.
- Secondary cerebral abscess formation following septic embolism is uncommon.
- Pulmonary abscesses rarely cause transcardiac septic embolism leading to cerebral infarction.
Observation:
- A case report details a patient with a pulmonary abscess.
- The abscess led to septic embolic cerebral infarction.
- The cerebral infarction subsequently transformed into a cerebral abscess.
Findings:
- This case represents the first reported instance of septic embolic ischemic stroke originating from a pulmonary abscess with secondary brain abscess formation.
- Successful management involved antibiotic therapy and abscess drainage.
- The patient showed significant symptom improvement and rehabilitation.
Implications:
- Pulmonary abscesses should be considered a potential source of septic embolic ischemic stroke.
- Prompt diagnosis and treatment, including early antibiotic therapy and regular cranial CT scans, are vital for detecting and managing secondary cerebral abscesses.
- This highlights the importance of considering unusual sources for embolic events in stroke patients.
Related Concept Videos
Brain Abscess l: Introduction
Pulmonary Embolism I: Introduction
Pulmonary Embolism I: Introduction
Hemorrhagic Stroke ll: Pathophysiology
Ischemic Stroke l: Introduction
Ischemic Stroke ll: Pathophysiology
