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Updated: May 17, 2026

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Clinical Imaging of Microwave Mammography
Published on: November 14, 2025
Measurements of system sharpness for two digital breast tomosynthesis systems
1Department of Radiology, UZ Gasthuisberg, Leuven, Belgium. nicholas.marshall@uzleuven.be
Physics in Medicine and Biology
|November 6, 2012
Summary
This study proposes sharpness parameters for digital breast tomosynthesis (DBT) systems, incorporating focus size and motion effects for quality assurance. Evaluating modulation transfer function (MTF) at various heights reveals system performance impacts.
Area of Science:
- Medical Imaging Physics
- Radiological Quality Assurance
- Digital Breast Tomosynthesis (DBT)
Background:
- Accurate assessment of imaging system sharpness is crucial for effective quality assurance in digital breast tomosynthesis (DBT).
- Existing quality assurance protocols may not fully account for the dynamic factors affecting image sharpness, such as X-ray focus size and motion.
- Understanding these factors is essential for optimizing diagnostic performance in DBT.
Purpose of the Study:
- To propose system sharpness parameters for DBT systems that integrate the influence of focus size and focus motion.
- To establish parameters suitable for routine quality assurance protocols in DBT imaging.
- To evaluate the impact of varying object height above the detector on imaging performance.
Main Methods:
- Measured X-ray focus size using a multiple pinhole test object.
- Determined detector presampling modulation transfer function (MTF) using a steel edge.
- Measured in-plane and in-depth MTF/PSF using tungsten wires and an aluminum bead within PMMA phantoms at varying heights.
Main Results:
- Modulation transfer function (MTF) at 0.50 cycles/mm (MTF(0.50)) decreased with increasing height above the table for both Siemens Inspiration and Hologic Selenia Dimensions systems.
- Measured MTF(0.50) values showed a maximum deviation of 13% from theoretically calculated values.
- In-depth point spread function (PSF) full-width half-maximum (FWHM) was 3.0 mm for Inspiration and 5.9 mm for Dimensions; 3D MTF was independent of bead height.
Conclusions:
- Evaluating MTF as a function of height above the table in both projection images and reconstructed planes provides critical insights into DBT system performance.
- The proposed sharpness parameters, considering focus size and motion, are valuable for quality assurance protocols.
- A 25 µm tungsten wire in a PMMA plate is suitable for measuring in-plane MTF.

