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Updated: May 17, 2026

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
Published on: April 27, 2017
Ethyl 2,4-dimethyl-pyrido[1,2-a]benz-imidazole-3-carboxyl-ate
Ai Guo Zhu1, Zhuo Ming Ma, Lin Jie Li
1School of Chemistry and Chemical Engineering, Taishan Medical University, Tai an 271016, People's Republic of China.
Abstract:
The title compound, C(16)H(16)N(2)O(2), was synthesized using a novel tandem annulation reaction between 1-(1H-benzo[d]imidazol-2-yl)ethanone and ethyl (E)-4-bromo-but-2-enoate under mild conditions. The dihedral angles formed by the mean plane of the five-membered imidazole ring with the dihydro-pyridin and benzene rings are 1.54 (9) and 1.85 (9)°, respectively.
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