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Active mobilization for mechanically ventilated patients: a systematic review
Zhiqiang Li1, Xiaoxia Peng, Bo Zhu
1Department of Critical Care Medicine, Fuxing Hospital, Capital Medical University, Beijing, China.
Archives of Physical Medicine and Rehabilitation
|November 7, 2012
Summary
Active mobilization may improve physical function and hospital outcomes for mechanically ventilated patients. Early initiation in the ICU is safe, but more research is needed due to study limitations.
Area of Science:
- Critical Care Medicine
- Physical Therapy
- Rehabilitation Science
Background:
- Mechanical ventilation exceeding 24 hours poses risks to physical function and hospital outcomes.
- Limited evidence exists on the benefits and safety of active mobilization in this patient population.
Purpose of the Study:
- To investigate the effectiveness and safety of active mobilization in patients requiring mechanical ventilation for over 24 hours.
Main Methods:
- A comprehensive literature search was conducted across multiple databases (PubMed, Embase, CINAHL, etc.).
- Included studies were randomized controlled trials, quasi-RCTs, comparative studies, and case series.
- Data extraction and quality assessment were performed independently by two reviewers.
Main Results:
- Active mobilization may enhance muscle strength, functional independence, and ventilator weaning.
- It may also reduce intensive care unit (ICU) and hospital length of stay.
- No serious adverse events were reported, and one study indicated reduced 1-year mortality.
Conclusions:
- Active mobilization shows promise for improving physical function and hospital outcomes in mechanically ventilated patients.
- Early implementation in the ICU is feasible and safe.
- Further high-quality research is necessary to confirm these findings due to heterogeneity and methodological limitations in current studies.
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