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Updated: May 17, 2026
08:43
Investigating Intestinal Inflammation in DSS-induced Model of IBD
Published on: February 1, 2012
Inflammatory bowel disease in central India: a single centre experience over five years
Ajay K Jain1, Shohini Sircar, Mayank Jain
1Department of Gastroenterology, Choithram Hospital and Research Centre, Indore, India.
Tropical Doctor
|November 7, 2012
Summary
This study analyzed inflammatory bowel disease (IBD) cases from 2005-2010. Ulcerative colitis was more common than Crohn's disease, with similar incidence and age at diagnosis across sexes.
Area of Science:
- Gastroenterology
- Epidemiology
- Internal Medicine
Background:
- Inflammatory bowel disease (IBD) encompasses chronic conditions like ulcerative colitis and Crohn's disease.
- Understanding the epidemiological characteristics of IBD is crucial for public health and clinical management.
- Previous data on IBD prevalence and demographics in our specific region were limited.
Purpose of the Study:
- To determine the incidence and demographic features of inflammatory bowel disease (IBD) in our population.
- To compare the prevalence of ulcerative colitis and Crohn's disease.
- To identify patterns in disease presentation and diagnosis.
Main Methods:
- Retrospective analysis of patient records.
- Inclusion criteria: patients diagnosed with IBD between 2005 and 2010.
- Data collected included diagnosis, sex, and age at diagnosis.
Main Results:
- Ulcerative colitis was significantly more prevalent than Crohn's disease.
- The incidence of IBD was similar between males and females.
- The age at diagnosis was comparable for both ulcerative colitis and Crohn's disease.
- Limited left-sided ulcerative colitis represented the most common subtype.
- Crohn's disease diagnosis was challenging, often misdiagnosed as tuberculosis.
Conclusions:
- Ulcerative colitis is the predominant form of IBD in our setting.
- Demographic profiles for ulcerative colitis and Crohn's disease show similarities in incidence and age at diagnosis.
- Diagnostic challenges for Crohn's disease necessitate improved recognition and diagnostic strategies.
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