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Related Concept Videos

Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions01:15

Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions

PK–PD modeling has significantly influenced FDA regulatory decisions, particularly drug approval, dosage optimization, and labeling. These models integrate pharmacokinetics (PK) and pharmacodynamics (PD) to predict drug behavior and effects, aiding in optimizing dosing regimens and enhancing the probability of clinical trial success.One notable example is Nesiritide (Natrecor®), a recombinant human brain natriuretic peptide for treating acute decompensated congestive heart failure (CHF).
Pharmacovigilance01:19

Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Pharmacokinetic–Pharmacodynamic Relationship: Exposure, Response and Effect01:26

Pharmacokinetic–Pharmacodynamic Relationship: Exposure, Response and Effect

The pharmacokinetic-pharmacodynamic (PK-PD) relationship describes the intricate link between drug exposure, efficacy, and toxicity, forming the foundation for optimal dosing regimens. This relationship uses mathematical modeling to characterize drug concentration-effect dynamics, ensuring precise therapeutic outcomes.Exposure represents the pharmacokinetic aspect of the PK-PD relationship, denoting the drug amount that elicits a biological response. It is typically quantified by administered...
Pharmacokinetic–Pharmacodynamic Relationship: Problems01:24

Pharmacokinetic–Pharmacodynamic Relationship: Problems

The empirical approach to drug therapy optimization relies on correlating pharmacological response with administered dosage. Such an approach can be costly, time-consuming, and often yields poor correlation due to variables like formulation factors and drug elimination characteristics. A more precise approach correlates response with plasma drug concentration or the amount of drug in the body, rather than dosage. This is achieved through pharmacokinetic-pharmacodynamic (PK/PD) modeling, which...
Preclinical Development: Overview01:28

Preclinical Development: Overview

Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...

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Related Experiment Video

Updated: May 17, 2026

Using Simulation Models to Train Clinicians in the Use of Point-of-Care Ultrasound
05:04

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Published on: August 9, 2024

Professional development webinars for pharmacists.

Eric C Buxton1, Erik C Burns, James E De Muth

  • 1School of Pharmacy, University of Wisconsin, Madison, WI 53705-2222, USA. ebuxton@pharmacy.wisc.edu

American Journal of Pharmaceutical Education
|November 7, 2012
PubMed
Summary

Pharmacists found continuing education webinars valuable and relevant, but attendance was limited. Future strategies will address scheduling to encourage repeat participation in these educational programs.

Keywords:
assessmentcontinuing educationdistance learninglifelong learningprofessional developmentwebinar

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Area of Science:

  • Continuing Education
  • Pharmacy Practice
  • Webinar Technology

Background:

  • Practicing pharmacists require timely and practical continuing education.
  • A series of webinars was developed to meet this need in a specific therapeutic area.

Purpose of the Study:

  • To assess pharmacist satisfaction with continuing education webinars.
  • To identify reasons for pharmacist enrollment in these webinars.

Main Methods:

  • Monthly webinars on a specific therapeutic area were presented throughout 2011.
  • Surveys were administered to pharmacists who completed at least one webinar.

Main Results:

  • Participants reported high satisfaction with webinar quality and delivery.
  • No significant demographic or enrollment reason differences were found between single and repeat attendees.

Conclusions:

  • Webinars were well-received for quality, value, and relevance.
  • Low average attendance per pharmacist necessitates strategies to improve repeat participation.
  • Addressing scheduling conflicts and other barriers is planned to boost engagement.