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Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
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Procedures for In Vitro Cultivation of Treponema pallidum, the Syphilis Spirochete
09:45

Procedures for In Vitro Cultivation of Treponema pallidum, the Syphilis Spirochete

Published on: January 24, 2025

Early prenatal syphilis.

Santosh Rathod1, Bela Shah

  • 1Department of Dermatology, B. J. Medical College, Civil Hospital, Ahmedabad, India.

Indian Dermatology Online Journal
|November 7, 2012
PubMed
Summary
This summary is machine-generated.

Congenital syphilis is a persistent challenge. A 2-month-old infant presented with classic symptoms, including skin lesions and bone changes, confirming prenatal syphilis transmission.

Keywords:
Prenatal syphilisserological screening

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Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Dermatology

Background:

  • Syphilis in pregnancy remains a global health concern, despite available diagnostics and treatments.
  • Early diagnosis and management are crucial to prevent congenital syphilis and its sequelae.

Observation:

  • A 2-month-old infant presented with rhinorrhea, papulosquamous lesions on palms and soles, and perianal erosions.
  • Physical examination revealed characteristic cutaneous and perianal lesions.
  • Radiographs showed early periosteal changes in the humerus and tibia.

Findings:

  • The infant's Serum Rapid Plasma Reagin (S.RPR) test was positive at 1:64 dilution.
  • The mother's S.RPR test was positive at 1:8 dilution.
  • These results confirmed the diagnosis of early congenital syphilis.

Implications:

  • This case highlights the importance of vigilant screening for syphilis in pregnant women.
  • Prompt diagnosis and treatment are essential to prevent severe outcomes in infants.
  • Continued public health efforts are needed to combat syphilis transmission during pregnancy.