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Early prenatal syphilis

Santosh Rathod1, Bela Shah

  • 1Department of Dermatology, B. J. Medical College, Civil Hospital, Ahmedabad, India.

Indian Dermatology Online Journal
|November 7, 2012
PubMed

Insights

Congenital syphilis is a persistent challenge. A 2-month-old infant presented with classic symptoms, including skin lesions and bone changes, confirming prenatal syphilis transmission.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Dermatology

Background:

  • Syphilis in pregnancy remains a global health concern, despite available diagnostics and treatments.
  • Early diagnosis and management are crucial to prevent congenital syphilis and its sequelae.

Observation:

  • A 2-month-old infant presented with rhinorrhea, papulosquamous lesions on palms and soles, and perianal erosions.
  • Physical examination revealed characteristic cutaneous and perianal lesions.
  • Radiographs showed early periosteal changes in the humerus and tibia.

Findings:

  • The infant's Serum Rapid Plasma Reagin (S.RPR) test was positive at 1:64 dilution.
  • The mother's S.RPR test was positive at 1:8 dilution.
  • These results confirmed the diagnosis of early congenital syphilis.

Implications:

  • This case highlights the importance of vigilant screening for syphilis in pregnant women.
  • Prompt diagnosis and treatment are essential to prevent severe outcomes in infants.
  • Continued public health efforts are needed to combat syphilis transmission during pregnancy.

Keywords:
Prenatal syphilisserological screening

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