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Updated: May 17, 2026
08:04
Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation
Published on: July 9, 2014
Herpes zoster duplex bilateralis in an immunocompetent host
Pratik Gahalaut1, Sandhya Chauhan
1Department of Dermatology, SRMSIMS, Bareilly, Uttar Pradesh, India.
Indian Dermatology Online Journal
|November 7, 2012
Summary
Herpes zoster duplex bilateralis (HZDB), a rare condition affecting different body sides, is presented in an immunocompetent individual. This case is likely the first reported instance of HZDB in India within this demographic.
Area of Science:
- Virology
- Dermatology
- Immunology
Background:
- Varicella zoster virus (VZV) is responsible for chickenpox and herpes zoster.
- Herpes zoster duplex bilateralis (HZDB) is a rare manifestation of VZV reactivation.
- HZDB typically affects immunosuppressed individuals or the elderly.
Observation:
- This report details a case of HZDB in an immunocompetent host.
- The patient presented with concurrent herpes zoster in two non-contiguous dermatomes on different sides of the body.
Findings:
- The occurrence of HZDB in an immunocompetent individual is exceptionally rare.
- This case represents a unique presentation of VZV reactivation.
Implications:
- This case expands the known clinical spectrum of herpes zoster duplex bilateralis.
- Further research may elucidate factors contributing to HZDB in immunocompetent hosts.
- Highlights the importance of considering rare VZV presentations in clinical practice.
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