Burden of acute, persistent and chronic diarrhea, Thailand, 2010

Sumitr Sutra1, Pensri Kosuwon, Aroon Chirawatkul

  • 1Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. sumitr@kku.ac.th

Insights

Childhood diarrhea in Thailand remains common, with millions of episodes annually. However, mortality is low, with risks linked to young age, persistent diarrhea, and underlying health conditions.

Area of Science:

  • Pediatric Infectious Diseases
  • Public Health Surveillance
  • Epidemiology

Background:

  • Diarrheal disease incidence in Thai children under five has risen over the past decade.
  • Childhood diarrhea mortality has significantly decreased, prompting evaluation of MCH services.

Purpose of the Study:

  • To assess the overall burden of childhood diarrheal diseases in Thailand.
  • To analyze the epidemiological patterns and risk factors associated with childhood diarrhea.

Main Methods:

  • Analysis of intestinal infectious diseases (ICD10: A00-A09) data, categorized into infectious diarrhea and dysentery.
  • Investigation included outpatient (OPD) and inpatient (IPD) visits, mortality, hospital stay duration, and co-morbidities.

Main Results:

  • The study identified 3.7 million diarrhea episodes, 756,552 OPD visits, and 124,403 IPD admissions.
  • Diarrheal incidence peaked during the cool and early rainy seasons.
  • Factors associated with persistent diarrhea included age, sepsis, malnutrition, and HIV; mortality risks involved infancy, septicemia, and dehydration.

Conclusions:

  • Diarrhea incidence in Thai children under five is higher than anticipated, despite low mortality rates.
  • Mortality is strongly associated with infants, persistent diarrhea, septicemia, and pre-existing chronic conditions.
Abstract

Related Concept Videos

Cholera01:25

Cholera

Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents01:18

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents01:20

Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents

Diarrhea is characterized by the occurrence of frequent, watery bowel movements. Various factors can trigger diarrhea, including viral or bacterial infections, foodborne illnesses, side effects from certain medications, and underlying digestive disorders. If not adequately managed, diarrhea can lead to complications such as dehydration, electrolyte imbalances, and nutrient deficiencies. Severe diarrhea can lead to significant weight loss, malnutrition, and weakened immune function.
Adsorbents...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...