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Child patterns of growth delay and cognitive development in a Bolivian mining city
María Ruiz-Castell1, Anne-Elie Carsin, Flavia-Laura Barbieri
1Department of Experimental and Health Sciences, Universitat Pompeu Fabra (UPF), Dr. Aiguader, 88 08003 Barcelona, Spain. m.ruizcastell@gmail.com
Insights
Infant growth patterns in Bolivia showed faster growth in smaller newborns, leading to higher weight by 12 months. This rapid infant growth did not impact cognitive development, even near mining industries.
Area of Science:
- Environmental Health
- Pediatrics
- Developmental Psychology
Background:
- Infant growth patterns are crucial for long-term health outcomes.
- Understanding the impact of environmental factors, such as mining industry proximity, on child development is essential.
- The ToxBol (Toxicity in Bolivia) birth cohort provides a unique dataset to study these relationships.
Purpose of the Study:
- To characterize infant growth patterns in the first year of life in a Bolivian cohort.
- To investigate the association between infant weight gain and cognitive development.
- To assess potential impacts of living near contaminated mining industries on child development.
Main Methods:
- Analysis of data from 175 children in the ToxBol birth cohort.
- Definition of rapid growth (weight z-score change > 0.67) and slow growth (weight z-score change < -0.67) in the first 6 months.
- Neurodevelopmental evaluation using the Bayley Scales of Infant Development; mixed models used for association analysis.
Main Results:
- Children with rapid growth weighed less at birth but had higher body mass index at 12 months.
- Rapid growth was not statistically associated with cognitive development after adjusting for confounding factors.
- The study found no significant link between infant growth patterns and cognitive outcomes in this cohort.
Conclusions:
- Smaller newborns in this Bolivian cohort exhibited faster growth, achieving greater weight and length by 12 months.
- Observed infant growth patterns did not negatively affect cognitive development.
- Environmental factors related to mining industries did not show a discernible impact on the studied growth-cognition relationship.
Objectives:
This study aims to (1) follow up and characterize infant growth patterns during the first year of life in Bolivia, and (2) determine whether there exists an association between weight gain and cognitive development in children living near contaminated mining industries.
Methods:
Data on 175 children participating to the ToxBol (Toxicity in Bolivia) birth cohort were analyzed. Rapid-growth during the first 6 months was defined as a change in weight z-score > 0.67 while slow-growth was defined as a weight z-score change of < -0.67. Neurodevelopment was evaluated using the Bayley Scales of Infant Development at 10.5-12.5 months of age. Mixed models were used to examine the association between cognitive development and weight gain.
Results:
Rapid growers weighed less at birth (P < 0.01). However, they revealed a higher body mass index at 12 months of age (0.70 ± 0.73, P < 0.01). After adjustment for confounding, rapid growth was not associated with cognitive development (coef = 0.49, 95% confidence interval = -4.10, 5.08).
Conclusions:
In this Bolivian cohort, children born smaller were more likely to grow/develop faster and attain greater weight and length. Their cognitive development was not affected by their growth patterns.
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