Related Experiment Video
Updated: May 17, 2026

09:24
Preparation of Meiotic Chromosome Spreads from Mouse Oocytes for Assessment of Synapsis and Recombination
Published on: July 18, 2025
Tinkering with meiosis
Wayne Crismani1, Chloé Girard, Raphael Mercier
1INRA, UMR1318, Institut Jean-Pierre Bourgin, RD10, F-78000 Versailles, France.
Journal of Experimental Botany
|November 9, 2012
Summary
Meiosis research has advanced our understanding of heredity, enabling new plant breeding techniques. This review explores manipulating meiosis for creating and propagating novel plant varieties.
Area of Science:
- Genetics and Plant Breeding
- Molecular Biology
- Cell Biology
Background:
- Meiosis is fundamental to Mendelian heredity.
- Recent advances have significantly deepened the understanding of meiotic processes.
- Progress has been made in characterizing genes involved in key meiotic events.
Purpose of the Study:
- To review advances in understanding meiosis.
- To focus on aspects of meiosis that can be manipulated for plant breeding.
- To discuss the creation and propagation of new plant varieties through meiotic manipulation.
Main Methods:
- Review of recent functional characterization of meiotic genes.
- Analysis of advances in genetic tools and knowledge bases.
- Focus on the practical application of meiotic research in plant breeding.
Main Results:
- Deeper knowledge of key meiotic events like recombination, cell cycle regulation, and chromosome distribution.
- Development of advanced tools and knowledge for manipulating meiosis.
- Identification of meiotic aspects amenable to plant breeding applications.
Conclusions:
- Advances in meiosis research offer significant potential for plant breeding.
- Targeted manipulation of meiotic processes can lead to the development of new varieties.
- Continued research is crucial for harnessing the full potential of meiotic manipulation in agriculture.
Related Concept Videos
Meiosis I
Meiosis is a carefully orchestrated set of cell divisions, the goal of which—in humans—is to produce haploid sperm or eggs, each containing half the number of chromosomes present in somatic cells elsewhere in the body. Meiosis I is the first such division, and involves several key steps, among them: condensation of replicated chromosomes in diploid cells; the pairing of homologous chromosomes and their exchange of information; and finally, the separation of homologous chromosomes by a...
Meiosis I
Meiosis is the division of a diploid cell into haploid cells forming sperm and eggs in animals through differentiation. Meiosis I is the first stage of meiosis, where the genetic recombination of homologous chromosomes and the reduction of the ploidy level by half occurs.
Prophase I is the most extended and complex step of meiosis I characterized by synapsis, chromosome pairing, and recombination of the homologous chromosomes. This process is facilitated by a proteinaceous structure called the...
Prophase I is the most extended and complex step of meiosis I characterized by synapsis, chromosome pairing, and recombination of the homologous chromosomes. This process is facilitated by a proteinaceous structure called the...
Meiosis I
Meiosis is the division of a diploid cell into haploid cells forming sperm and eggs in animals through differentiation. Meiosis I is the first stage of meiosis, where the genetic recombination of homologous chromosomes and the reduction of the ploidy level by half occurs.
Prophase I is the most extended and complex step of meiosis I characterized by synapsis, chromosome pairing, and recombination of the homologous chromosomes. This process is facilitated by a proteinaceous structure called the...
Prophase I is the most extended and complex step of meiosis I characterized by synapsis, chromosome pairing, and recombination of the homologous chromosomes. This process is facilitated by a proteinaceous structure called the...
Meiosis II
Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23 chromosomes—one from each homologous initial pair. Importantly, each chromosome in these cells is composed of two joined copies, and when these cells enter meiosis II, the goal is to separate such sister chromatids using the same microtubule-based network employed in other division processes. The result of meiosis II is two haploid cells, each containing...
Meiosis II
Meiosis II entails cell division and segregation of the sister chromatids, resulting in the production of four unique haploid gametes. The steps for meiosis II are similar to mitosis, except that meiosis II occurs in haploid cells, whereas mitosis occurs in diploid cells.
The timing and cell division patterns of meiosis differ between males and females. In male meiosis, the centrosomes are part of the formation of the meiotic spindle. However, in oocytes, including that of humans, Drosophila,...
The timing and cell division patterns of meiosis differ between males and females. In male meiosis, the centrosomes are part of the formation of the meiotic spindle. However, in oocytes, including that of humans, Drosophila,...
Meiosis II
Meiosis II entails cell division and segregation of the sister chromatids, resulting in the production of four unique haploid gametes. The steps for meiosis II are similar to mitosis, except that meiosis II occurs in haploid cells, whereas mitosis occurs in diploid cells.
The timing and cell division patterns of meiosis differ between males and females. In male meiosis, the centrosomes are part of the formation of the meiotic spindle. However, in oocytes, including that of humans, Drosophila,...
The timing and cell division patterns of meiosis differ between males and females. In male meiosis, the centrosomes are part of the formation of the meiotic spindle. However, in oocytes, including that of humans, Drosophila,...

