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Published on: September 13, 2019
Primary undifferentiated penile sarcoma in adolescence
Young Hoon Choi1, Hyeon Woo Kim, Jae Hyun Ahn
1Department of Urology, Pusan National University Hospital, Busan, Korea.
Korean Journal of Urology
|November 9, 2012
Summary
A rare case of primary penile undifferentiated sarcoma in a young man was successfully treated. This penile cancer, characterized by small round cell sarcoma with neuroendocrine features, showed a positive response to surgery and chemotherapy.
Area of Science:
- Oncology
- Urologic Oncology
- Pathology
Background:
- Primary penile sarcoma is a rare malignancy.
- Undifferentiated sarcoma with neuroendocrine differentiation is an aggressive subtype.
- Penile masses require thorough diagnostic evaluation.
Purpose of the Study:
- To report a case of primary penile undifferentiated sarcoma in an adolescent.
- To highlight the diagnostic and therapeutic challenges of this rare tumor.
- To discuss the clinical course and outcome.
Main Methods:
- Case presentation of a 16-year-old male with a penile mass.
- Diagnostic workup including magnetic resonance imaging (MRI) and histopathological examination.
- Treatment involved tumorectomy and systemic chemotherapy.
Main Results:
- A 5x5 cm penile mass was diagnosed as small round cell sarcoma with neuroendocrine differentiation.
- Metastatic pulmonary nodules were identified.
- The patient remained alive with no evidence of recurrence or metastasis 34 months post-diagnosis.
Conclusions:
- Primary penile undifferentiated sarcoma is a rare but aggressive malignancy.
- Multimodality treatment including surgery and chemotherapy can be effective.
- Early diagnosis and comprehensive management are crucial for favorable outcomes.
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