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Published on: November 9, 2016
Anal bulking agents for faecal incontinence.
N F S Watson1, A Koshy, P M Sagar
1The John Goligher Colorectal Unit, St James's University Hospital, Leeds, UK.
Summary
Anal bulking agents, including various biomaterials, offer a promising treatment for fecal incontinence. Studies show significant symptom improvement in over 50% of patients with mild to moderate cases.
Area of Science:
- Gastroenterology
- Colorectal Surgery
- Biomaterials Science
Background:
- Fecal incontinence (FI) is a prevalent condition impacting quality of life.
- Current treatment options for FI have limitations, necessitating novel therapeutic approaches.
Purpose of the Study:
- To systematically review and evaluate the efficacy of anal bulking agents in treating fecal incontinence.
- To assess the various biomaterials utilized for anal bulking and their reported outcomes.
Main Methods:
- A systematic literature review was conducted to identify relevant studies on anal bulking agents.
- Studies reporting on the use of diverse biomaterials for anal bulking were analyzed.
Main Results:
- A wide array of biomaterials, including autologous fat, collagen, and synthetic microspheres, have been employed.
- Most studies report significant improvement in continence for 50% of patients with mild to moderate FI.
- Minimal associated morbidity was observed with the use of these agents.
Conclusions:
- Anal bulking agents represent a viable treatment option for alleviating symptoms of fecal seepage and soilage.
- Further research may clarify optimal injection sites and mechanisms of action for these agents.
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