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Tuberculous hypertrophic pachymeningitis presenting as visual blurring and headaches
1Advanced Radiology Clinic, Off MA Jinnah Road, Karachi. drrukhsanatariq@hotmail.com
Abstract:
Hypertrophic cranial pachymeningitis is a rare chronic fibrosing inflammatory disease characterised by localized or diffuse thickening of duramater, leptomeninges, and tentorium. The etiology is diverse and includes infectious, granulomatous and inflammatory disorders, collagen vascular disorders, carcinoma, lymphoma, meningioma en plaque, sarcoidosis, haemodialysis, mucopolysaccharidosis, intrathecal drug administration, and meningeal carcinomatosis diseases. Intracranial hypotension is also an important image mimicker. Most often patients present with complaint of headache, vomiting, cranial nerve palsy, ataxia, raised intracranial pressure and focal neurological deficit. Other signs and symptoms are inconstant and variable. The imaging features of hypertrophic cranial pachymeningitis include dural thickening, dural mass, sinus thrombosis, venous congestion with white matter changes. Extensive preoperative imaging studies usually are essential by Computerised Tomography (CT) or Magnetic Resonance Imaging (MRI). The radiological findings may be characteristic of hypertrophic cranial pachymeningitis, may not divulge the underlying etiology. Meningeal biopsy is essential for diagnosing the cause. We reviewed a case of a tuberculous hypertrophic cranial pachymeningitis.
Insights
Hypertrophic cranial pachymeningitis involves thickening of the dura mater. Diagnosis requires meningeal biopsy to identify diverse causes, including tuberculosis.
Area of Science:
- Neurology
- Pathology
Background:
- Hypertrophic cranial pachymeningitis (HCP) is a rare chronic inflammatory condition causing dural thickening.
- Its etiology is diverse, encompassing infections, autoimmune disorders, malignancies, and other conditions.
Observation:
- Patients commonly present with headaches, vomiting, cranial nerve palsies, and neurological deficits.
- Imaging reveals dural thickening, masses, sinus thrombosis, and venous congestion with white matter changes.
Findings:
- Radiological findings can suggest HCP but often do not reveal the underlying cause.
- Meningeal biopsy is crucial for definitive diagnosis and etiological determination.
Implications:
- Understanding the diverse causes of HCP is vital for appropriate patient management.
- This review highlights a case of tuberculous HCP, emphasizing the need for comprehensive etiological investigation.
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