Related Experiment Video
Updated: May 17, 2026

Culture of Bladder Cancer Organoids as Precision Medicine Tools
Published on: December 28, 2021
Adolescent urologic oncology: current issues and future directions.
Nicholas G Cost1, Carrye R Cost2, James I Geller2
1Division of Pediatric Urology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Adolescent cancer incidence is rising, yet receives less research and funding than pediatric cancer. This review highlights unique challenges and future directions in adolescent urologic oncology.
Area of Science:
- Urologic Oncology
- Adolescent Medicine
- Cancer Epidemiology
Background:
- Adolescent cancer incidence is increasing, surpassing pediatric rates.
- Adolescent oncology, particularly urologic oncology, is under-researched and underfunded compared to pediatric oncology.
- Adolescent urologic oncology presents unique challenges at the intersection of pediatric and adult care.
Purpose of the Study:
- To review key adolescent urologic oncologic diagnoses.
- To discuss critical issues including fertility, radiation, surveillance, secondary malignancies, chemotherapy effects, and psychosocial burden.
- To identify future research directions and obstacles in adolescent urologic oncology.
Main Methods:
- Review of recent Surveillance Epidemiology and End Results (SEER) data.
- Synthesis of current literature on adolescent urologic oncology.
- Focus on specific diagnoses: testicular germ cell malignancy, genitourinary rhabdomyosarcoma, and renal malignancies.
Main Results:
- Adolescent urologic oncology requires a distinct approach due to unique disease processes and patient needs.
- Significant therapeutic impacts on fertility, radiation exposure, and long-term health consequences are noted.
- Psychosocial burden is a critical, often overlooked, aspect of adolescent cancer care.
Conclusions:
- Adolescent urologic oncology is a distinct field demanding specialized attention and research.
- Addressing fertility, long-term effects, and psychosocial support is crucial for this population.
- Future research must overcome obstacles to achieve progress comparable to pediatric urologic oncology.
More Related Videos
06:39Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma
Published on: November 22, 2019
07:25A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Related Concept Videos
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Urinary Tract Calculi III: Medical Management
Urinary Tract Calculi VI: Surgical Management
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Urologic Endoscopic Procedure: Cystoscopic Examination
Targeted Cancer Therapies
There are several types of targeted therapies against specific...