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Updated: May 17, 2026
14:06
Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays
Published on: November 12, 2012
EcoCyc: fusing model organism databases with systems biology.
Ingrid M Keseler1, Amanda Mackie, Martin Peralta-Gil
1SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025, USA. keseler@ai.sri.com
Nucleic Acids Research
|November 13, 2012
Summary
EcoCyc is a manually curated database detailing Escherichia coli K-12 MG1655 biology. Ongoing updates and new web tools enhance its utility for research and education.
Area of Science:
- Microbiology
- Bioinformatics
- Genomics
Background:
- EcoCyc is a comprehensive biological database for Escherichia coli K-12 MG1655.
- It relies on expert manual curation of gene product functions from experimental literature.
Purpose of the Study:
- To describe the current state and ongoing development of the EcoCyc database.
- To highlight enhancements in data content and web-based tools.
Main Methods:
- Manual curation of Escherichia coli K-12 gene product functions.
- Integration of information from the experimental literature.
- Development of web-based tools and resources.
Main Results:
- EcoCyc provides an updated and comprehensive view of E. coli biology.
- New tools enhance the usability and accessibility of the database.
- EcoCyc is increasingly utilized as an educational resource.
Conclusions:
- EcoCyc remains a valuable resource for understanding Escherichia coli.
- Continuous updates and tool development improve its utility for researchers and educators.
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