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Circulating natriuretic peptide concentrations in hyperthyroid cats
P Menaut1, D J Connolly, A Volk
1Department of Veterinary Clinical Sciences, The Royal Veterinary College, North Mymms, Hertfordshire, UK.
Objectives:
To assess the influence of thyroid function on natriuretic peptide concentration in hyperthyroid cats before and after treatment.
Methods:
Serum natriuretic peptide concentration was measured in 61 hyperthyroid cats recruited from first-opinion clinics before and after treatment.
Results:
Following successful treatment, total thyroxine, heart rate, systolic blood pressure and packed cell volume all decreased and bodyweight and creatinine concentrations increased. Furthermore, a significant (P < 0·001) decline in NT-proBNP concentration but not NT-proANP was identified.
Clinical Significance:
Thyroid function has a modest but significant effect on NT-proBNP concentration. Thyroid status should be taken into account when interpreting NT-proBNP concentrations in cats.
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