Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and the...
Atomic Absorption Spectroscopy: Instrumentation01:22

Atomic Absorption Spectroscopy: Instrumentation

An atomic absorption spectrophotometer (AAS) comprises several components: a radiation source, an atomizer, a monochromator, and a detector. The radiation source can be a hollow-cathode lamp (HCL) or an electrodeless-discharge lamp (EDL), both of which provide a narrow emission line of the required wavelength. However, some instruments use continuum sources and high-resolution monochromators to achieve a narrow range of radiation.
The atomizer used in AAS can be either a flame atomizer or an...
Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation01:26

Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation

Inductively coupled plasma (ICP) is the common plasma source used in atomic emission spectroscopy (AES), a technique that detects and analyzes various elements in a sample. This method is often called inductively coupled plasma atomic emission spectroscopy (ICP-AES).
There are three main types of inductively coupled plasma atomic emission spectroscopy  (ICP-AES) instruments: sequential, simultaneous multichannel, and Fourier transform instruments, with the latter being less commonly used.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quality by digital design in action: a workflow for crystallisation and isolation.

International journal of pharmaceutics·2025
Same author

Quality by digital design to accelerate sustainable medicines development.

International journal of pharmaceutics·2025
Same author

Calibration free approaches for rapid polymorph discrimination <i>via</i> low frequency (THz) Raman spectroscopy.

Chemical communications (Cambridge, England)·2024
Same author

A Mechanistic Investigation of the <i>N</i>-Hydroxyphthalimide Catalyzed Benzylic Oxidation Mediated by Sodium Chlorite.

The Journal of organic chemistry·2024
Same author

Multicenter evaluation of the Selux Next-Generation Phenotyping antimicrobial susceptibility testing system.

Journal of clinical microbiology·2023
Same author

Optical Screening and Classification of Drug Binding to Proteins in Human Blood Serum.

Analytical chemistry·2023

Related Experiment Video

Updated: May 16, 2026

Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging
09:46

Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging

Published on: April 28, 2022

Automated cosmic spike filter optimized for process Raman spectroscopy.

Sergey Mozharov1, Alison Nordon, David Littlejohn

  • 1Applied Physics Laboratory, University of Washington, Seattle, 98105, USA. sergey@apl.uw.edu

Applied Spectroscopy
|November 14, 2012
PubMed
Summary

A new automated method accurately detects cosmic spikes in process Raman spectroscopy data. This approach overcomes limitations of existing techniques, offering reliable spike removal without user-defined parameters.

More Related Videos

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
09:57

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

Published on: July 25, 2022

Related Experiment Videos

Last Updated: May 16, 2026

Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging
09:46

Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging

Published on: April 28, 2022

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
09:57

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

Published on: July 25, 2022

Area of Science:

  • Analytical Chemistry
  • Spectroscopy

Background:

  • Cosmic spikes are artifacts in Raman data that require removal.
  • Existing spike removal methods are often unsuitable for process Raman spectroscopy due to time, accuracy, or parameter-dependency issues.

Purpose of the Study:

  • To develop and validate a novel, automated method for detecting cosmic spikes in process Raman spectroscopy data.

Main Methods:

  • A multistage spike recognition algorithm was developed.
  • The algorithm tracks sharp intensity changes in the time domain.
  • It distinguishes cosmic spikes from spectral noise and Raman peak variations.

Main Results:

  • The novel method accurately detects both high and low intensity cosmic spikes.
  • It effectively differentiates spikes from other spectral features.
  • The procedure is free from user-defined parameters and operates automatically.

Conclusions:

  • The developed method provides a reliable and automated solution for cosmic spike removal in process Raman spectroscopy.
  • It overcomes the limitations of existing algorithms, enhancing data analysis efficiency and accuracy.