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Updated: May 16, 2026

The Forced Swim Test as a Model of Depressive-like Behavior
Published on: March 2, 2015
[Elephantiasis nostras verrucosa in a patient with major depressive disorder]
J Simón Llanes1, I Coll Vilar, C Tamarit Francés
1Unidad Hospitalaria de Rehabilitación, Hospital Psiquiátrico Universitario Institut Pere Mata, Reus, España.
Abstract:
Elephantiasis nostras verrucosa is a rare condition characterised by papules, verrucous lesions, fibrosis and deformity of the affected area. It is caused by chronic lymphedema that could be congenital or produced by a non-associated infection (such as tuberculosis, mycotic infection, syphilis), surgery, radiotherapy, trauma, neoplastic obstruction, obesity, portal hypertension, or congestive heart failure. There is no standard treatment for this rare skin disorder. Depending on the cause and the severity, the treatment can be medical or surgical. We report the case of a man seen in our hospital with a major depression and elephantiasis nostras verrucosa skin lesions on both legs, who was successfully treated with surgical debridement and conservative measures.
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