Related Experiment Video
Updated: May 16, 2026
Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
Published on: December 15, 2014
Initial experience of 3 tesla apparent diffusion coefficient values in differentiating benign and malignant thyroid
A Turan Ilica1, Hakan Artaş, Asli Ayan
1Department of Radiology, Gulhane Military Medical Faculty, Ankara, Turkey. aturca2002@yahoo.com
Purpose:
To evaluate the role of diffusion-weighted magnetic resonance imaging (DWMRI) in differentiating benign and malignant thyroid nodules using a 3 Tesla (T) MRI scanner.
Materials And Methods:
Twenty-eight nodules in 25 patients and 14 healthy control cases were included in the study. DWMRI was acquired with 6 b values with a 3T MRI scanner. The apparent diffusion coefficient (ADC) values of the nodules were calculated from reconstructed ADC map images and were compared with the final histopathological diagnoses.
Results:
The mean ADC value of the benign nodules was 1548 ± 353.4 (×10(-6) mm(2) /s), and the mean ADC of the malignant nodules was 814 ± 177.12 (×10(-6) mm(2) /s). The normal thyroid tissue had a mean ADC value of 1323.43 ± 210.35 × 10(-6) mm(2) /s (958-1689 × 10(-6) mm(2) /s) in the healthy control group. The ADC values were significantly different among the three groups (P = 0.001). An ADC value of 905 × 10(-6) mm(2) /s was determined to be the cutoff value for differentiating benign and malignant nodules, with 90% (55.5-98.3) sensitivity and 100% (81.3-100.0) specificity.
Conclusion:
This study suggests that the ADC values of nodules measured with a 3T MRI scanner could help in differentiating benign thyroid nodules from malignant nodules.
