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Related Experiment Video

Updated: May 16, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Current concepts in refractory migraine.

Elliott Schulman1, Brian E McGeeney

  • 1Lankenau Medical Center and Lankenau Institute for Medical Research, 100 Lancaster Avenue, Wynnewood, PA, 19096, USA, esmdha@gmail.com.

Current Treatment Options in Neurology
|November 15, 2012
PubMed
Summary
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Refractory or Intractable Migraine (RM) presents a significant challenge for healthcare providers. This article outlines comprehensive treatment strategies, emphasizing wellness and multimodal approaches to reduce disability in RM patients.

Area of Science:

  • Neurology
  • Headache Medicine

Background:

  • Refractory or Intractable Migraine (RM) is a recognized clinical challenge.
  • No formal diagnostic criteria currently exist for RM.
  • Existing treatments often fail to adequately manage RM patients.

Purpose of the Study:

  • To provide evidence-based and empiric treatment approaches for RM.
  • To outline strategies for reducing disability in RM patients.
  • To emphasize a holistic approach to managing RM.

Main Methods:

  • Review of current treatment modalities for RM.
  • Emphasis on wellness, including mood, stress, sleep, and trigger avoidance.
  • Integration of preventive and "rescue" treatment plans.
  • Consideration of comorbid conditions and medication overuse (MOH).

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Related Experiment Videos

Last Updated: May 16, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies
05:49

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies

Published on: November 1, 2024

Investigating Migraine-Like Behavior Using Light Aversion in Mice
05:23

Investigating Migraine-Like Behavior Using Light Aversion in Mice

Published on: August 11, 2021

Main Results:

  • Multimodal treatment strategies improve outcomes.
  • Wellness, including optimizing mood, sleep, and stress management, is foundational.
  • Addressing comorbidities and avoiding medication overuse are crucial.
  • OnabotulinumtoxinA and neurostimulation offer additional therapeutic options.

Conclusions:

  • A comprehensive, individualized approach combining various modalities is essential for managing RM.
  • A strong physician-patient relationship enhances treatment compliance and outcomes.
  • Long-term management requires ongoing physician-patient interaction and cooperation.
  • Multidisciplinary teams are beneficial for RM patients with multiple comorbidities.