Ganglioneuroblastoma in a young child with Turner syndrome
Jordan E Pinsker1, David F Crudo
1Division of Pediatric Endocrinology, Department of Pediatrics, Tripler Army Medical Center, Mail Code MCHK-PE, 1 Jarrett White Road, Honolulu, HI 96859-5000, USA. jordan.pinsker@us.army.mil
Journal of Pediatric Endocrinology & Metabolism : JPEM
|November 20, 2012
Abstract:
X chromosome aneuploidy has been identified as a potential risk factor for the development of neuroblastic tumors. We report a case of a 4-year-old girl with a 45,X karyotype incidentally discovered to have a large ganglioneuroblastoma on initial screening ultrasound. The incidence of these tumors in girls with Turner syndrome as well as their possible relationship to recombinant human growth hormone treatment is discussed.
