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A Simplified Technique for Producing an Ischemic Wound Model
Published on: May 2, 2012
Hyperbaric oxygen and wound healing
Sourabh Bhutani1, Guruswamy Vishwanath
1Principal Medical Officer, INS Shankul, c/o Fleet Mail Office, Colaba, Mumbai, India.
Summary
Hyperbaric oxygen therapy (HBOT) offers significant benefits as an adjunctive treatment for various non-healing and infected wounds. Its approved applications include diabetic ulcers, radiation injuries, and traumatic conditions, making it essential for comprehensive wound management.
Area of Science:
- Medicine
- Therapeutics
Background:
- Hyperbaric oxygen therapy (HBOT) involves administering 100% oxygen at pressures exceeding atmospheric levels.
- HBOT is an established adjunctive therapy with several approved indications.
Purpose of the Study:
- To review the established applications and benefits of HBOT in wound healing and other conditions.
- To highlight the expanding role of HBOT in managing complex wounds.
Main Methods:
- Review of existing studies and clinical trials on HBOT applications.
- Analysis of HBOT's efficacy in various wound types and radiation-induced injuries.
Main Results:
- HBOT is effective for non-healing wounds like diabetic and vascular insufficiency ulcers.
- Approved indications include infected wounds (e.g., Fournier's gangrene), traumatic injuries, and radiation-induced conditions (e.g., osteoradionecrosis).
Conclusions:
- HBOT is a valuable adjunctive therapy for a range of challenging wounds.
- Increased chamber availability and evidence support considering HBOT in wound management strategies.
Keywords:
Air embolismcompartment syndromecrush syndromedecompression sicknessdiabetes mellitusdiabetic footgas gangrenehyperbarichyperbaric medicinehyperbaric oxygen therapyhyperbaric oxygenationnecrotising fasciitisosteomyelitisosteoradionecrosisradiation injuriesradiation necrosisreperfusion injurysoft tissue infectionssurgical flapstranscutaneous oximetryMore Related Videos
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