Related Experiment Video
Updated: May 16, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Strabismus in craniosynostosis
Jamie B Rosenberg1, Oren M Tepper, Norman B Medow
1Division of Pediatric Ophthalmology, Department of Ophthalmology, Montefiore Medical Center, Bronx, New York, USA. Jamiebella78@gmail.com
Abstract:
Strabismus is common in craniosynostosis, with rates from 39% to 90.9% in Crouzon, Apert, Pfeiffer, and Saethre-Chotzen syndromes. This article reviews the epidemiology of strabismus in these disorders and discusses competing theories of the mechanism, including absent muscles, excyclorotation of muscles, and instability of muscle pulleys. The authors then review options for surgical treatment of the often complex ocular misalignment in these disorders.
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