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Updated: May 16, 2026

Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer
Published on: March 14, 2019
Angiogenesis-related microRNAs in colon cancer
1Fourth Military Medical University, Xijing Hospital of Digestive Diseases, State Key Laboratory of Cancer Biology, Shaanxi Province, China. hongliu180@126.com
Introduction:
Angiogenesis, for its fundamental role in cancer growth and metastasis, has become an appealing target in cancer therapy. A number of angiogenesis-related microRNAs (miRNAs) are under investigation and they can affect the cancerous phenotype of malignant cells.
Areas Covered:
The authors review the recent advances in angiogenesis-related miRNAs in human colon cancer. They also envisage future developments toward potential miRNA-based applications to cancer treatment.
Expert Opinion:
Angiogenesis-related miRNAs may reasonably be considered as a valuable cancer therapeutic tool. More investigations should be performed to promote therapeutic-clinical research of miRNAs in patients with colon cancer.
Insights
Angiogenesis-related microRNAs (miRNAs) show promise as a therapeutic strategy for colon cancer by targeting tumor growth and metastasis. Further research is needed to advance miRNA-based treatments for patients.
Area of Science:
- Oncology
- Molecular Biology
- Genetics
Background:
- Angiogenesis is crucial for cancer progression, making it a key therapeutic target.
- MicroRNAs (miRNAs) are regulators of cellular processes and influence cancer phenotypes.
Purpose of the Study:
- To review recent advancements in angiogenesis-related miRNAs in human colon cancer.
- To explore future directions for miRNA-based cancer therapies.
Main Methods:
- Literature review of current research on angiogenesis and miRNAs in colon cancer.
- Analysis of the potential of miRNAs as therapeutic agents.
Main Results:
- Angiogenesis-related miRNAs play a significant role in colon cancer development.
- These miRNAs can modulate the cancerous phenotype of malignant cells.
Conclusions:
- Angiogenesis-related miRNAs represent a promising therapeutic avenue for colon cancer.
- Additional clinical research is required to fully realize the therapeutic potential of miRNAs in colon cancer patients.
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