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Related Concept Videos

Diabetic Foot Ulcer01:31

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Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory neuropathy reduces pain perception,...
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Diabetic Neuropathy

DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...
Fractures: Bone Repair01:27

Fractures: Bone Repair

Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
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Complications of Diabetes Mellitus01:22

Complications of Diabetes Mellitus

Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency, resistance, or both. Prolonged hyperglycemia disrupts metabolic homeostasis and leads to acute and chronic complications.Acute ComplicationsAcute complications result from sudden metabolic imbalance.Diabetic ketoacidosis (DKA) mainly appears in type 1 diabetes but may also develop in type 2 diabetes, particularly under extreme stress. It arises from severe insulin deficiency,...
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Diabetic Retinopathy

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Updated: May 16, 2026

Assessment of Bone Fracture Healing Using Micro-Computed Tomography
12:04

Assessment of Bone Fracture Healing Using Micro-Computed Tomography

Published on: December 9, 2022

Diabetic calcaneal fractures.

Bryan A Sagray1, John J Stapleton, Thomas Zgonis

  • 1Division of Podiatric Medicine and Surgery, Department of Orthopaedic Surgery, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive MSC 7776, San Antonio, TX 78229, USA.

Clinics in Podiatric Medicine and Surgery
|November 21, 2012
PubMed
Summary

Diabetic calcaneal fractures are complex injuries with high complication risks like infection and limb loss. Careful management is crucial to improve outcomes for these severe foot fractures.

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Last Updated: May 16, 2026

Assessment of Bone Fracture Healing Using Micro-Computed Tomography
12:04

Assessment of Bone Fracture Healing Using Micro-Computed Tomography

Published on: December 9, 2022

Area of Science:

  • Orthopedic surgery
  • Diabetic foot complications
  • Traumatology

Background:

  • Calcaneal fractures in diabetic patients present unique challenges.
  • Increased complication rates, including poor wound healing and infection, are common.
  • These complications can lead to significant morbidity and potential limb loss.

Purpose of the Study:

  • To review the management strategies for calcaneal fractures in the diabetic population.
  • To discuss the specific complications associated with these injuries.
  • To evaluate the outcomes of treating diabetic calcaneal fractures.

Main Methods:

  • Review of current literature on diabetic calcaneal fracture management.
  • Analysis of complication rates and risk factors.
  • Evaluation of conservative and surgical treatment outcomes.

Main Results:

  • Diabetic calcaneal fractures are associated with higher complication rates than in non-diabetic patients.
  • Complications include delayed healing, deep infections, malunion, and Charcot neuroarthropathy.
  • Effective management strategies are essential to mitigate risks and improve limb salvage.

Conclusions:

  • Management of calcaneal fractures in diabetics requires meticulous attention due to elevated risks.
  • Early and appropriate intervention can reduce morbidity and prevent limb loss.
  • Further research into optimized treatment protocols is warranted.